Safety and efficacy of add-on intra-arterial thrombolysis after intravenous thrombolysis and mechanical thrombectomy in patients with ischemic stroke and cerebral vessel occlusion

Safety and efficacy of add-on intra-arterial thrombolysis after intravenous thrombolysis and mechanical thrombectomy in patients with ischemic stroke and cerebral vessel occlusion

IntroductionFor acute ischemic stroke (AIS) with large vessel occlusion (LVO), the currently established treatment strategy of combined intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT) is not sufficiently effective in all patients. Intra-arterial thrombolysis (IAT) as an adjunct to...

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Bibliographic Details
Main Authors: Norma J. Diel, Kai Bernhard Woelk, Anne Mrochen, Oliver Posner, Andre Worm, Omar Alhaj Omar, Christian Claudi, Patrick Schramm, Tobias Struffert, Hagen B. Huttner
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Neurology
Subjects:
acute ischemic stroke
intravenous thrombolysis
endovascular treatment
intraarterial thrombolysis
mechanical thrombectomy
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1560045/full
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