Erythrocyte Micronuclei and Nuclear Abnormalities in Three Species of Fish from Lake Piediluco (Central Italy)

The frequencies of both micronuclei (Mn) and nuclear abnormalities (NAs) were determined in peripheral blood smears of European perch (<i>Perca fluviatilis)</i>, rudd (<i>Scardinius erythrophthalmus)</i>, and pikes (genus <i>Esox</i>) from Lake Piediluco (Central...

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Main Authors: Valentina Battistelli, Leonardo Brustenga, Gianandrea La Porta, Mattia Baccianella, Livia Lucentini
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Limnological Review
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Online Access:https://www.mdpi.com/2300-7575/25/2/19
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author Valentina Battistelli
Leonardo Brustenga
Gianandrea La Porta
Mattia Baccianella
Livia Lucentini
author_facet Valentina Battistelli
Leonardo Brustenga
Gianandrea La Porta
Mattia Baccianella
Livia Lucentini
author_sort Valentina Battistelli
collection DOAJ
description The frequencies of both micronuclei (Mn) and nuclear abnormalities (NAs) were determined in peripheral blood smears of European perch (<i>Perca fluviatilis)</i>, rudd (<i>Scardinius erythrophthalmus)</i>, and pikes (genus <i>Esox</i>) from Lake Piediluco (Central Italy). Given the conformation of the lake, all the animals from the three species were equally exposed to the same natural stressors. To assess the different stress responses in the three species, 20 blood smears per specimen from each species were analyzed, counting the micronuclei and nuclear aberration present over a total of 1000 erythrocytes for each slide. Different responses to stress were recorded in the three species, with <i>P. fluviatilis</i> exhibiting the least amount of both Mn (0.42%) and NAs (0.01%), and therefore the better homeostasis, while the majority of Mn and NAs were recorded in <i>Esox</i> spp. (Mn: 3.88%; NAs: 23.18%). No MN were observed in <i>S. erythrophthalmus, so</i> that might not be an adequate species to apply the micronucleus test, and it also presented a lower percentage of NAs (15.32%) compared to the pike samples. This work provides, for the first time, baseline values of erythrocyte micronuclei and nuclear aberration from natural populations of the three fish species in a lake from Central Italy.
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spelling doaj-art-28c72369bb0c4e8988fb19e769eb96912025-08-20T03:27:30ZengMDPI AGLimnological Review2300-75752025-05-012521910.3390/limnolrev25020019Erythrocyte Micronuclei and Nuclear Abnormalities in Three Species of Fish from Lake Piediluco (Central Italy)Valentina Battistelli0Leonardo Brustenga1Gianandrea La Porta2Mattia Baccianella3Livia Lucentini4Department of Chemistry Biology and Biotechnology, University of Perugia, 06126 Perugia, ItalyDepartment of Chemistry Biology and Biotechnology, University of Perugia, 06126 Perugia, ItalyDepartment of Chemistry Biology and Biotechnology, University of Perugia, 06126 Perugia, ItalyDepartment of Chemistry Biology and Biotechnology, University of Perugia, 06126 Perugia, ItalyDepartment of Chemistry Biology and Biotechnology, University of Perugia, 06126 Perugia, ItalyThe frequencies of both micronuclei (Mn) and nuclear abnormalities (NAs) were determined in peripheral blood smears of European perch (<i>Perca fluviatilis)</i>, rudd (<i>Scardinius erythrophthalmus)</i>, and pikes (genus <i>Esox</i>) from Lake Piediluco (Central Italy). Given the conformation of the lake, all the animals from the three species were equally exposed to the same natural stressors. To assess the different stress responses in the three species, 20 blood smears per specimen from each species were analyzed, counting the micronuclei and nuclear aberration present over a total of 1000 erythrocytes for each slide. Different responses to stress were recorded in the three species, with <i>P. fluviatilis</i> exhibiting the least amount of both Mn (0.42%) and NAs (0.01%), and therefore the better homeostasis, while the majority of Mn and NAs were recorded in <i>Esox</i> spp. (Mn: 3.88%; NAs: 23.18%). No MN were observed in <i>S. erythrophthalmus, so</i> that might not be an adequate species to apply the micronucleus test, and it also presented a lower percentage of NAs (15.32%) compared to the pike samples. This work provides, for the first time, baseline values of erythrocyte micronuclei and nuclear aberration from natural populations of the three fish species in a lake from Central Italy.https://www.mdpi.com/2300-7575/25/2/19micronucleinuclear aberrationenvironmental stresshomeostasis
spellingShingle Valentina Battistelli
Leonardo Brustenga
Gianandrea La Porta
Mattia Baccianella
Livia Lucentini
Erythrocyte Micronuclei and Nuclear Abnormalities in Three Species of Fish from Lake Piediluco (Central Italy)
Limnological Review
micronuclei
nuclear aberration
environmental stress
homeostasis
title Erythrocyte Micronuclei and Nuclear Abnormalities in Three Species of Fish from Lake Piediluco (Central Italy)
title_full Erythrocyte Micronuclei and Nuclear Abnormalities in Three Species of Fish from Lake Piediluco (Central Italy)
title_fullStr Erythrocyte Micronuclei and Nuclear Abnormalities in Three Species of Fish from Lake Piediluco (Central Italy)
title_full_unstemmed Erythrocyte Micronuclei and Nuclear Abnormalities in Three Species of Fish from Lake Piediluco (Central Italy)
title_short Erythrocyte Micronuclei and Nuclear Abnormalities in Three Species of Fish from Lake Piediluco (Central Italy)
title_sort erythrocyte micronuclei and nuclear abnormalities in three species of fish from lake piediluco central italy
topic micronuclei
nuclear aberration
environmental stress
homeostasis
url https://www.mdpi.com/2300-7575/25/2/19
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