Pre-Transport Salt Baths Mitigate Physiological Stress and Tissue Damage in Channel Catfish (<i>Ictalurus punctatus</i>) Fingerlings: Evidence from Multi-Biomarker Assessment and Histopathology

Effective transport strategies are critical for the survival and welfare of juvenile <i>Ictalurus punctatus</i>, but the effects of pre-transport salt bath treatments remain uncertain. In this study, we systematically evaluated the effects of pre-transport salt bath acclimation at 0‰ (S1...

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Main Authors: Guowei Huang, Haohua Li, Juguang Wang, Tao Liao, Liang Qiu, Guangquan Xiong, Lan Wang, Chan Bai, Yu Zhang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/15/2249
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author Guowei Huang
Haohua Li
Juguang Wang
Tao Liao
Liang Qiu
Guangquan Xiong
Lan Wang
Chan Bai
Yu Zhang
author_facet Guowei Huang
Haohua Li
Juguang Wang
Tao Liao
Liang Qiu
Guangquan Xiong
Lan Wang
Chan Bai
Yu Zhang
author_sort Guowei Huang
collection DOAJ
description Effective transport strategies are critical for the survival and welfare of juvenile <i>Ictalurus punctatus</i>, but the effects of pre-transport salt bath treatments remain uncertain. In this study, we systematically evaluated the effects of pre-transport salt bath acclimation at 0‰ (S1), 1‰ (S2), 5‰ (S3), and 9‰ (S4) salinity for 30 min on stress resilience and recovery in fingerlings during 12 h of simulated transport and 24 h of recovery. All fish survived, but total ammonia nitrogen (TAN) increased, and pH decreased in all groups, except S3, which showed significantly lower TAN and higher pH (<i>p</i> < 0.05). The S3 and S4 groups showed attenuated increases in serum cortisol and glucose, with S3 exhibiting the fastest return to baseline levels and stable serum sodium and potassium levels. Liver antioxidant enzyme activities in group S3 remained stable, with the lowest malondialdehyde (MDA) accumulation. Integrated biomarker response (IBR) and histological analyses demonstrated that S3 had the lowest systemic stress and tissue damage, whereas S1 and S4 displayed marked cellular disruption. These results indicate that a 5‰ salt bath applied prior to transport may improve water quality, mitigate stress responses, and preserve tissue integrity in juvenile channel catfish. Further studies are needed to confirm these findings in other species and under commercial transport conditions.
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spelling doaj-art-28a6d2c92a8240a2a2e31faaffa9372e2025-08-20T03:02:48ZengMDPI AGAnimals2076-26152025-07-011515224910.3390/ani15152249Pre-Transport Salt Baths Mitigate Physiological Stress and Tissue Damage in Channel Catfish (<i>Ictalurus punctatus</i>) Fingerlings: Evidence from Multi-Biomarker Assessment and HistopathologyGuowei Huang0Haohua Li1Juguang Wang2Tao Liao3Liang Qiu4Guangquan Xiong5Lan Wang6Chan Bai7Yu Zhang8School of Life Sciences and Health Engineering, Hubei University of Technology, Wuhan 430068, ChinaKey Laboratory of Cold Chain Logistics Technology for Agro-Product, Ministry of Agriculture and Rural Affairs, Institute of Agro-Product Processing and Nuclear Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaKey Laboratory of Cold Chain Logistics Technology for Agro-Product, Ministry of Agriculture and Rural Affairs, Institute of Agro-Product Processing and Nuclear Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaKey Laboratory of Cold Chain Logistics Technology for Agro-Product, Ministry of Agriculture and Rural Affairs, Institute of Agro-Product Processing and Nuclear Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaKey Laboratory of Cold Chain Logistics Technology for Agro-Product, Ministry of Agriculture and Rural Affairs, Institute of Agro-Product Processing and Nuclear Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaKey Laboratory of Cold Chain Logistics Technology for Agro-Product, Ministry of Agriculture and Rural Affairs, Institute of Agro-Product Processing and Nuclear Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaKey Laboratory of Cold Chain Logistics Technology for Agro-Product, Ministry of Agriculture and Rural Affairs, Institute of Agro-Product Processing and Nuclear Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaKey Laboratory of Cold Chain Logistics Technology for Agro-Product, Ministry of Agriculture and Rural Affairs, Institute of Agro-Product Processing and Nuclear Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, ChinaSchool of Life Sciences and Health Engineering, Hubei University of Technology, Wuhan 430068, ChinaEffective transport strategies are critical for the survival and welfare of juvenile <i>Ictalurus punctatus</i>, but the effects of pre-transport salt bath treatments remain uncertain. In this study, we systematically evaluated the effects of pre-transport salt bath acclimation at 0‰ (S1), 1‰ (S2), 5‰ (S3), and 9‰ (S4) salinity for 30 min on stress resilience and recovery in fingerlings during 12 h of simulated transport and 24 h of recovery. All fish survived, but total ammonia nitrogen (TAN) increased, and pH decreased in all groups, except S3, which showed significantly lower TAN and higher pH (<i>p</i> < 0.05). The S3 and S4 groups showed attenuated increases in serum cortisol and glucose, with S3 exhibiting the fastest return to baseline levels and stable serum sodium and potassium levels. Liver antioxidant enzyme activities in group S3 remained stable, with the lowest malondialdehyde (MDA) accumulation. Integrated biomarker response (IBR) and histological analyses demonstrated that S3 had the lowest systemic stress and tissue damage, whereas S1 and S4 displayed marked cellular disruption. These results indicate that a 5‰ salt bath applied prior to transport may improve water quality, mitigate stress responses, and preserve tissue integrity in juvenile channel catfish. Further studies are needed to confirm these findings in other species and under commercial transport conditions.https://www.mdpi.com/2076-2615/15/15/2249salt bathjuvenile <i>Ictalurus punctatus</i>simulated transporttransport efficiency
spellingShingle Guowei Huang
Haohua Li
Juguang Wang
Tao Liao
Liang Qiu
Guangquan Xiong
Lan Wang
Chan Bai
Yu Zhang
Pre-Transport Salt Baths Mitigate Physiological Stress and Tissue Damage in Channel Catfish (<i>Ictalurus punctatus</i>) Fingerlings: Evidence from Multi-Biomarker Assessment and Histopathology
Animals
salt bath
juvenile <i>Ictalurus punctatus</i>
simulated transport
transport efficiency
title Pre-Transport Salt Baths Mitigate Physiological Stress and Tissue Damage in Channel Catfish (<i>Ictalurus punctatus</i>) Fingerlings: Evidence from Multi-Biomarker Assessment and Histopathology
title_full Pre-Transport Salt Baths Mitigate Physiological Stress and Tissue Damage in Channel Catfish (<i>Ictalurus punctatus</i>) Fingerlings: Evidence from Multi-Biomarker Assessment and Histopathology
title_fullStr Pre-Transport Salt Baths Mitigate Physiological Stress and Tissue Damage in Channel Catfish (<i>Ictalurus punctatus</i>) Fingerlings: Evidence from Multi-Biomarker Assessment and Histopathology
title_full_unstemmed Pre-Transport Salt Baths Mitigate Physiological Stress and Tissue Damage in Channel Catfish (<i>Ictalurus punctatus</i>) Fingerlings: Evidence from Multi-Biomarker Assessment and Histopathology
title_short Pre-Transport Salt Baths Mitigate Physiological Stress and Tissue Damage in Channel Catfish (<i>Ictalurus punctatus</i>) Fingerlings: Evidence from Multi-Biomarker Assessment and Histopathology
title_sort pre transport salt baths mitigate physiological stress and tissue damage in channel catfish i ictalurus punctatus i fingerlings evidence from multi biomarker assessment and histopathology
topic salt bath
juvenile <i>Ictalurus punctatus</i>
simulated transport
transport efficiency
url https://www.mdpi.com/2076-2615/15/15/2249
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