Abstract 260: TCD Bubble test as a Screening tool for detection of Patent Foramen Ovale in Stroke

Introduction Introduction & Objectives: Transcranial Doppler (TCD) ultrasound provides rapid, noninvasive, real‐time measures of cerebrovascular function. Patent Foramen Ovale (PFO) is fourfold more common in Young Stroke Patients <55 years of age, as opposed to age‐matched controls. The PFO...

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Main Authors: Danish Ahammed PK, Paul Alapatt, Aiswarya Raj, Ashraf VV, Shafeed Mattummal
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Stroke: Vascular and Interventional Neurology
Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.260
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author Danish Ahammed PK
Paul Alapatt
Aiswarya Raj
Ashraf VV
Shafeed Mattummal
author_facet Danish Ahammed PK
Paul Alapatt
Aiswarya Raj
Ashraf VV
Shafeed Mattummal
author_sort Danish Ahammed PK
collection DOAJ
description Introduction Introduction & Objectives: Transcranial Doppler (TCD) ultrasound provides rapid, noninvasive, real‐time measures of cerebrovascular function. Patent Foramen Ovale (PFO) is fourfold more common in Young Stroke Patients <55 years of age, as opposed to age‐matched controls. The PFO test with TCD, often called a “TCD bubble test,” involves the intravenous injection of micro‐bubbles (air mixed with saline), which can be detected by a TCD system in the Middle Cerebral artery (MCA). The TCD Bubble test, hence, can be used as a screening test in the evaluation of Embolic Stroke Of Undetermined Source. Methods A retrospective observational study was carried out at Aster MIMS Hospital, Kozhikode, where 63 patients with Young stroke were evaluated between April 2021 and October 2022. Along with routine stroke workup, including Transthoracic Echocardiography, TCD bubble tests were performed to detect Right to left shunt. Further, Transesophageal Echocardiography was done to look for Patent Foramen Ovale in TCD Bubble test positive patients. Results TCD Bubble test was detected to be positive in 36 patients and negative in 27 patients. Transesophageal Echocardiography performed in TCD Positive patients confirmed PFO in 35 out of 36 patients. Transthoracic echocardiography, however, could detect PFO only in 10 patients. Conclusion TCD Bubble test can be employed as a screening tool in the evaluation of young stroke to detect Patent Foramen Ovale with efficacy similar to TEE.
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spelling doaj-art-28a4cde12efb40068c5025e4e908dccb2025-08-20T03:13:36ZengWileyStroke: Vascular and Interventional Neurology2694-57462023-11-013S210.1161/SVIN.03.suppl_2.260Abstract 260: TCD Bubble test as a Screening tool for detection of Patent Foramen Ovale in StrokeDanish Ahammed PK0Paul Alapatt1Aiswarya Raj2Ashraf VV3Shafeed Mattummal4Aster Malabar Institute Of Medical Sciences Kerala IndiaAster Malabar Institute Of Medical Sciences Kerala IndiaAster Malabar Institute Of Medical Sciences Kerala IndiaAster Malabar Institute Of Medical Sciences Kerala IndiaAster Malabar Institute Of Medical Sciences Kerala IndiaIntroduction Introduction & Objectives: Transcranial Doppler (TCD) ultrasound provides rapid, noninvasive, real‐time measures of cerebrovascular function. Patent Foramen Ovale (PFO) is fourfold more common in Young Stroke Patients <55 years of age, as opposed to age‐matched controls. The PFO test with TCD, often called a “TCD bubble test,” involves the intravenous injection of micro‐bubbles (air mixed with saline), which can be detected by a TCD system in the Middle Cerebral artery (MCA). The TCD Bubble test, hence, can be used as a screening test in the evaluation of Embolic Stroke Of Undetermined Source. Methods A retrospective observational study was carried out at Aster MIMS Hospital, Kozhikode, where 63 patients with Young stroke were evaluated between April 2021 and October 2022. Along with routine stroke workup, including Transthoracic Echocardiography, TCD bubble tests were performed to detect Right to left shunt. Further, Transesophageal Echocardiography was done to look for Patent Foramen Ovale in TCD Bubble test positive patients. Results TCD Bubble test was detected to be positive in 36 patients and negative in 27 patients. Transesophageal Echocardiography performed in TCD Positive patients confirmed PFO in 35 out of 36 patients. Transthoracic echocardiography, however, could detect PFO only in 10 patients. Conclusion TCD Bubble test can be employed as a screening tool in the evaluation of young stroke to detect Patent Foramen Ovale with efficacy similar to TEE.https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.260
spellingShingle Danish Ahammed PK
Paul Alapatt
Aiswarya Raj
Ashraf VV
Shafeed Mattummal
Abstract 260: TCD Bubble test as a Screening tool for detection of Patent Foramen Ovale in Stroke
Stroke: Vascular and Interventional Neurology
title Abstract 260: TCD Bubble test as a Screening tool for detection of Patent Foramen Ovale in Stroke
title_full Abstract 260: TCD Bubble test as a Screening tool for detection of Patent Foramen Ovale in Stroke
title_fullStr Abstract 260: TCD Bubble test as a Screening tool for detection of Patent Foramen Ovale in Stroke
title_full_unstemmed Abstract 260: TCD Bubble test as a Screening tool for detection of Patent Foramen Ovale in Stroke
title_short Abstract 260: TCD Bubble test as a Screening tool for detection of Patent Foramen Ovale in Stroke
title_sort abstract 260 tcd bubble test as a screening tool for detection of patent foramen ovale in stroke
url https://www.ahajournals.org/doi/10.1161/SVIN.03.suppl_2.260
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