Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healing

In experiment we studied influence of collagen, filled with platelet-rich plasma (PRP), on rats' bone regeneration in distal humerus. Used dose of PRP contained 130–135 pg/ml platelet-derived growth factor (PDGF). According to this level of PDGF, PRP-collagen treatment rapidly enhanced trabecul...

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Main Authors: A. Yu. Vaza, M. S. Makarov, V. V. Slastinin, N. V. Borovkova, I. Yu. Klyukvin, D. Yu. Pokhitonov, I. N. Ponomarev
Format: Article
Language:English
Published: N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department 2016-06-01
Series:Трансплантология (Москва)
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Online Access:https://www.jtransplantologiya.ru/jour/article/view/121
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author A. Yu. Vaza
M. S. Makarov
V. V. Slastinin
N. V. Borovkova
I. Yu. Klyukvin
D. Yu. Pokhitonov
I. N. Ponomarev
author_facet A. Yu. Vaza
M. S. Makarov
V. V. Slastinin
N. V. Borovkova
I. Yu. Klyukvin
D. Yu. Pokhitonov
I. N. Ponomarev
author_sort A. Yu. Vaza
collection DOAJ
description In experiment we studied influence of collagen, filled with platelet-rich plasma (PRP), on rats' bone regeneration in distal humerus. Used dose of PRP contained 130–135 pg/ml platelet-derived growth factor (PDGF). According to this level of PDGF, PRP-collagen treatment rapidly enhanced trabecular bones' growth, stimu-lated angiogenesis and reduced intensity of inflammation. Allogenic PRP, addressed to all experimental animals, allowed to make humerus healing 2 times shorter.
format Article
id doaj-art-28a02da4c17c4246a50fbc09bf13db8d
institution Kabale University
issn 2074-0506
2542-0909
language English
publishDate 2016-06-01
publisher N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
record_format Article
series Трансплантология (Москва)
spelling doaj-art-28a02da4c17c4246a50fbc09bf13db8d2025-08-20T03:56:37ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092016-06-01023644121Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healingA. Yu. Vaza0M. S. Makarov1V. V. Slastinin2N. V. Borovkova3I. Yu. Klyukvin4D. Yu. Pokhitonov5I. N. Ponomarev6N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department, MoscowIn experiment we studied influence of collagen, filled with platelet-rich plasma (PRP), on rats' bone regeneration in distal humerus. Used dose of PRP contained 130–135 pg/ml platelet-derived growth factor (PDGF). According to this level of PDGF, PRP-collagen treatment rapidly enhanced trabecular bones' growth, stimu-lated angiogenesis and reduced intensity of inflammation. Allogenic PRP, addressed to all experimental animals, allowed to make humerus healing 2 times shorter.https://www.jtransplantologiya.ru/jour/article/view/121platelet rich plasmaplatelets with granulespdgfosteogenesis
spellingShingle A. Yu. Vaza
M. S. Makarov
V. V. Slastinin
N. V. Borovkova
I. Yu. Klyukvin
D. Yu. Pokhitonov
I. N. Ponomarev
Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healing
Трансплантология (Москва)
platelet rich plasma
platelets with granules
pdgf
osteogenesis
title Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healing
title_full Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healing
title_fullStr Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healing
title_full_unstemmed Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healing
title_short Effi ciency of allogenic platelet-rich plasmsa, combined with collagen, in rat's humerus injury healing
title_sort effi ciency of allogenic platelet rich plasmsa combined with collagen in rat s humerus injury healing
topic platelet rich plasma
platelets with granules
pdgf
osteogenesis
url https://www.jtransplantologiya.ru/jour/article/view/121
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AT msmakarov efficiencyofallogenicplateletrichplasmsacombinedwithcollageninratshumerusinjuryhealing
AT vvslastinin efficiencyofallogenicplateletrichplasmsacombinedwithcollageninratshumerusinjuryhealing
AT nvborovkova efficiencyofallogenicplateletrichplasmsacombinedwithcollageninratshumerusinjuryhealing
AT iyuklyukvin efficiencyofallogenicplateletrichplasmsacombinedwithcollageninratshumerusinjuryhealing
AT dyupokhitonov efficiencyofallogenicplateletrichplasmsacombinedwithcollageninratshumerusinjuryhealing
AT inponomarev efficiencyofallogenicplateletrichplasmsacombinedwithcollageninratshumerusinjuryhealing