The global burden of vascular intestinal diseases: results from the 2021 Global Burden of Disease Study and projections using Bayesian age-period-cohort analysis

Background: Vascular intestinal disease is a major health concern that often requires emergency surgery in patients with intestinal obstruction, perforation, or bowel necrosis. We aimed to provide data on the incidence, prevalence, mortality and disability-adjusted life years (DALYs) of vascular int...

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Main Authors: Xiqiang Zhang, Longchao Wu, Yu Li, Ze Tao, Na Li, Haoyang Zhang, Ming Ren, Kexin Wang
Format: Article
Language:English
Published: Komiyama Printing Co. Ltd 2024-12-01
Series:Environmental Health and Preventive Medicine
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Online Access:https://www.jstage.jst.go.jp/article/ehpm/29/0/29_24-00206/_html/-char/en
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author Xiqiang Zhang
Longchao Wu
Yu Li
Ze Tao
Na Li
Haoyang Zhang
Ming Ren
Kexin Wang
author_facet Xiqiang Zhang
Longchao Wu
Yu Li
Ze Tao
Na Li
Haoyang Zhang
Ming Ren
Kexin Wang
author_sort Xiqiang Zhang
collection DOAJ
description Background: Vascular intestinal disease is a major health concern that often requires emergency surgery in patients with intestinal obstruction, perforation, or bowel necrosis. We aimed to provide data on the incidence, prevalence, mortality and disability-adjusted life years (DALYs) of vascular intestinal diseases from 1990 to 2021, thereby contributing to the development of health policies. Methods: Using standardized methods from the 2021 Global Burden of Disease study, we analyzed the incidence, prevalence, mortality, and DALYs of vascular intestinal disease from the perspectives of the sociodemographic index (SDI), regional, and country, along with the corresponding estimated annual percentage changes. Additionally, we used join-point regression to identify the key time points for disease burden changes. Results: In 2021, a total of 169,432 cases [95% uncertainty interval (UI): 155,127–185,189] of vascular intestinal disease were identified worldwide. The age-standardized incidence rate decreased from 18.81 (95% UI: 16.07–21.73) in 1990 to 15.98 (95% UI: 13.99–19.10) in 2021. In 2021, the age-standardized mortality rate was 1.12/100,000 people (95% UI: 1.00–1.21). Over the 32-year period, the global DALYs rate declined by 1.44 (95% Confidence Interval: −1.55 to −1.34). Within the five SDI regions, the high-middle SDI areas recorded the peak standardized mortality rates in 2021. Regionally, the greatest increase in incidence occurred in North Africa and the Middle East. Canada recorded the greatest national incidence rate [58.35 (95% UI: 50.05–67.37)] in 2021 among 204 countries, while Russia exhibited the highest related mortality [5.64/100,000 people (95% UI: 5.19–6.11)] and DALYs rate [101.48/100,000 people (95% UI: 93.83–109.66)]. Conclusions: Despite a global decline in the burden of vascular intestinal disease from 1990 to 2021, significant regional and national disparities persist and the disease burden among the elderly has increased.
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spelling doaj-art-289ed9023bba4a30a2ea7e5b8b3560282025-08-20T01:57:48ZengKomiyama Printing Co. LtdEnvironmental Health and Preventive Medicine1342-078X1347-47152024-12-0129717110.1265/ehpm.24-00206ehpmThe global burden of vascular intestinal diseases: results from the 2021 Global Burden of Disease Study and projections using Bayesian age-period-cohort analysisXiqiang Zhang0Longchao Wu1Yu Li2Ze Tao3Na Li4Haoyang Zhang5Ming Ren6Kexin Wang7The First Clinical College, Shandong UniversityThe First Clinical College, Shandong UniversityDepartment of General Surgery, Qilu Hospital of Shandong UniversityThe First Clinical College, Shandong UniversityDepartment of General Surgery, Qilu Hospital of Shandong UniversityThe First Clinical College, Shandong UniversityThe First Clinical College, Shandong UniversityDepartment of General Surgery, Qilu Hospital of Shandong UniversityBackground: Vascular intestinal disease is a major health concern that often requires emergency surgery in patients with intestinal obstruction, perforation, or bowel necrosis. We aimed to provide data on the incidence, prevalence, mortality and disability-adjusted life years (DALYs) of vascular intestinal diseases from 1990 to 2021, thereby contributing to the development of health policies. Methods: Using standardized methods from the 2021 Global Burden of Disease study, we analyzed the incidence, prevalence, mortality, and DALYs of vascular intestinal disease from the perspectives of the sociodemographic index (SDI), regional, and country, along with the corresponding estimated annual percentage changes. Additionally, we used join-point regression to identify the key time points for disease burden changes. Results: In 2021, a total of 169,432 cases [95% uncertainty interval (UI): 155,127–185,189] of vascular intestinal disease were identified worldwide. The age-standardized incidence rate decreased from 18.81 (95% UI: 16.07–21.73) in 1990 to 15.98 (95% UI: 13.99–19.10) in 2021. In 2021, the age-standardized mortality rate was 1.12/100,000 people (95% UI: 1.00–1.21). Over the 32-year period, the global DALYs rate declined by 1.44 (95% Confidence Interval: −1.55 to −1.34). Within the five SDI regions, the high-middle SDI areas recorded the peak standardized mortality rates in 2021. Regionally, the greatest increase in incidence occurred in North Africa and the Middle East. Canada recorded the greatest national incidence rate [58.35 (95% UI: 50.05–67.37)] in 2021 among 204 countries, while Russia exhibited the highest related mortality [5.64/100,000 people (95% UI: 5.19–6.11)] and DALYs rate [101.48/100,000 people (95% UI: 93.83–109.66)]. Conclusions: Despite a global decline in the burden of vascular intestinal disease from 1990 to 2021, significant regional and national disparities persist and the disease burden among the elderly has increased.https://www.jstage.jst.go.jp/article/ehpm/29/0/29_24-00206/_html/-char/englobal burden of diseasevascular intestinal diseaseestimated annual percentage changeaverage annual percentage changesocio-demographic index
spellingShingle Xiqiang Zhang
Longchao Wu
Yu Li
Ze Tao
Na Li
Haoyang Zhang
Ming Ren
Kexin Wang
The global burden of vascular intestinal diseases: results from the 2021 Global Burden of Disease Study and projections using Bayesian age-period-cohort analysis
Environmental Health and Preventive Medicine
global burden of disease
vascular intestinal disease
estimated annual percentage change
average annual percentage change
socio-demographic index
title The global burden of vascular intestinal diseases: results from the 2021 Global Burden of Disease Study and projections using Bayesian age-period-cohort analysis
title_full The global burden of vascular intestinal diseases: results from the 2021 Global Burden of Disease Study and projections using Bayesian age-period-cohort analysis
title_fullStr The global burden of vascular intestinal diseases: results from the 2021 Global Burden of Disease Study and projections using Bayesian age-period-cohort analysis
title_full_unstemmed The global burden of vascular intestinal diseases: results from the 2021 Global Burden of Disease Study and projections using Bayesian age-period-cohort analysis
title_short The global burden of vascular intestinal diseases: results from the 2021 Global Burden of Disease Study and projections using Bayesian age-period-cohort analysis
title_sort global burden of vascular intestinal diseases results from the 2021 global burden of disease study and projections using bayesian age period cohort analysis
topic global burden of disease
vascular intestinal disease
estimated annual percentage change
average annual percentage change
socio-demographic index
url https://www.jstage.jst.go.jp/article/ehpm/29/0/29_24-00206/_html/-char/en
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