Diagnosis and Prevalence (1975–2010) of Sudden Death due to Atlantoaxial Subluxation in Cervical Rheumatoid Arthritis: A Literature Review
Rheumatoid arthritis (RA), a chronic inflammatory disease primarily affecting synovial joints and tendons, can potentially impact various organs within the body. One notable complication associated with RA is upper cervical spine instability, medically termed atlantoaxial subluxation (AAS). This con...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2023/6675489 |
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| author | Eko Agus Subagio Pandu Wicaksono Muhammad Faris Abdul Hafid Bajamal Diaz Syafrie Abdillah |
| author_facet | Eko Agus Subagio Pandu Wicaksono Muhammad Faris Abdul Hafid Bajamal Diaz Syafrie Abdillah |
| author_sort | Eko Agus Subagio |
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| description | Rheumatoid arthritis (RA), a chronic inflammatory disease primarily affecting synovial joints and tendons, can potentially impact various organs within the body. One notable complication associated with RA is upper cervical spine instability, medically termed atlantoaxial subluxation (AAS). This condition can lead to adverse consequences, including chronic myelopathy and acute mechanical compression of the medulla oblongata, with the potential for sudden death. While AAS may often remain asymptomatic, some nonspecific symptoms, such as neck pain, have been documented. Severe atlantoaxial subluxation can trigger more distinct symptoms, including delayed occipital pain attributed to the compression of the exiting C2 nerve root. Recent studies have elucidated a spectrum of symptoms preceding sudden death, encompassing vertigo, dizziness, convulsions, dysphagia, disorientation, and seizures. Remarkably, some cases have reported sudden death occurring during sleep. Historical data reveal a fluctuating incidence of this phenomenon, with eleven cases reported between 1969 and 1975 and six cases documented between 1990 and 2010. Notably, one of the most prevalent causes of sudden mortality in individuals with RA is the acute mechanical damage inflicted upon the medulla oblongata due to atlantoaxial subluxation. |
| format | Article |
| id | doaj-art-2898853018404da49e31e1cfdf1b3de2 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-2898853018404da49e31e1cfdf1b3de22025-08-20T03:54:47ZengWileyThe Scientific World Journal1537-744X2023-01-01202310.1155/2023/6675489Diagnosis and Prevalence (1975–2010) of Sudden Death due to Atlantoaxial Subluxation in Cervical Rheumatoid Arthritis: A Literature ReviewEko Agus Subagio0Pandu Wicaksono1Muhammad Faris2Abdul Hafid Bajamal3Diaz Syafrie Abdillah4Department of NeurosurgeryDepartment of NeurosurgeryDepartment of NeurosurgeryDepartment of NeurosurgeryFaculty of MedicineRheumatoid arthritis (RA), a chronic inflammatory disease primarily affecting synovial joints and tendons, can potentially impact various organs within the body. One notable complication associated with RA is upper cervical spine instability, medically termed atlantoaxial subluxation (AAS). This condition can lead to adverse consequences, including chronic myelopathy and acute mechanical compression of the medulla oblongata, with the potential for sudden death. While AAS may often remain asymptomatic, some nonspecific symptoms, such as neck pain, have been documented. Severe atlantoaxial subluxation can trigger more distinct symptoms, including delayed occipital pain attributed to the compression of the exiting C2 nerve root. Recent studies have elucidated a spectrum of symptoms preceding sudden death, encompassing vertigo, dizziness, convulsions, dysphagia, disorientation, and seizures. Remarkably, some cases have reported sudden death occurring during sleep. Historical data reveal a fluctuating incidence of this phenomenon, with eleven cases reported between 1969 and 1975 and six cases documented between 1990 and 2010. Notably, one of the most prevalent causes of sudden mortality in individuals with RA is the acute mechanical damage inflicted upon the medulla oblongata due to atlantoaxial subluxation.http://dx.doi.org/10.1155/2023/6675489 |
| spellingShingle | Eko Agus Subagio Pandu Wicaksono Muhammad Faris Abdul Hafid Bajamal Diaz Syafrie Abdillah Diagnosis and Prevalence (1975–2010) of Sudden Death due to Atlantoaxial Subluxation in Cervical Rheumatoid Arthritis: A Literature Review The Scientific World Journal |
| title | Diagnosis and Prevalence (1975–2010) of Sudden Death due to Atlantoaxial Subluxation in Cervical Rheumatoid Arthritis: A Literature Review |
| title_full | Diagnosis and Prevalence (1975–2010) of Sudden Death due to Atlantoaxial Subluxation in Cervical Rheumatoid Arthritis: A Literature Review |
| title_fullStr | Diagnosis and Prevalence (1975–2010) of Sudden Death due to Atlantoaxial Subluxation in Cervical Rheumatoid Arthritis: A Literature Review |
| title_full_unstemmed | Diagnosis and Prevalence (1975–2010) of Sudden Death due to Atlantoaxial Subluxation in Cervical Rheumatoid Arthritis: A Literature Review |
| title_short | Diagnosis and Prevalence (1975–2010) of Sudden Death due to Atlantoaxial Subluxation in Cervical Rheumatoid Arthritis: A Literature Review |
| title_sort | diagnosis and prevalence 1975 2010 of sudden death due to atlantoaxial subluxation in cervical rheumatoid arthritis a literature review |
| url | http://dx.doi.org/10.1155/2023/6675489 |
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