Coverage and evaluation survey of post-mass drug administration for lymphatic filariasis in four endemic districts of Uttar Pradesh: Are we on the track?
Background & objectives: There is a persistent high microfilaria rate and variable reporting of coverage of Mass Drug Administration (MDA). This study aims to estimate the coverage, effective coverage, and compliance of drugs administered under MDA and determine the predictors affecting effectiv...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | Journal of Vector Borne Diseases |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/JVBD.JVBD_102_24 |
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| author | Sourabh Paul Aswani Kumar Seth Neeraj Pawar Abhay Singh Mukesh Shukla Bhola Nath |
| author_facet | Sourabh Paul Aswani Kumar Seth Neeraj Pawar Abhay Singh Mukesh Shukla Bhola Nath |
| author_sort | Sourabh Paul |
| collection | DOAJ |
| description | Background & objectives:
There is a persistent high microfilaria rate and variable reporting of coverage of Mass Drug Administration (MDA). This study aims to estimate the coverage, effective coverage, and compliance of drugs administered under MDA and determine the predictors affecting effective coverage.
Methods:
A community-based cross-sectional study was conducted in Amethi, Lucknow, Raebareli and Sultanpur districts of Uttar Pradesh, India. The study participants were selected using multi-stage random sampling using Probability Proportional to Estimated Size (PPES). The coverage, effective coverage and compliance of drugs were presented as proportion. The multivariable logistic regression model was applied to identify the significant predictors for effective coverage.
Results:
Of 4151 participants, 997 (24.0%), 340 (8.2%), 1158 (27.9%) and 1656 (39.9%) belonged to Amethi, Lucknow, Raebareli and Sultanpur districts, respectively. The coverage ranged from 49.8% to 87.9% and effective coverage ranged from 51.8% to 73.2% across districts. The compliance was the poorest (70.7%) in Sultanpur. The source of information about MDA, gender of the study participants and area of residence emerged as predictors for effective coverage in the districts.
Interpretation & conclusion:
The effective coverage was poor with good drug compliance across the districts. There is a need for a well-designed pre-MDA campaign addressing the fear of side effects of drugs and emphasizing the presence of the community during the MDA round along with monitoring and evaluation of the round. |
| format | Article |
| id | doaj-art-2897ec39a2254bd8b4e170bd82c8367e |
| institution | Kabale University |
| issn | 0972-9062 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Vector Borne Diseases |
| spelling | doaj-art-2897ec39a2254bd8b4e170bd82c8367e2025-08-20T03:29:44ZengWolters Kluwer Medknow PublicationsJournal of Vector Borne Diseases0972-90622025-04-0162217218010.4103/JVBD.JVBD_102_24Coverage and evaluation survey of post-mass drug administration for lymphatic filariasis in four endemic districts of Uttar Pradesh: Are we on the track?Sourabh PaulAswani Kumar SethNeeraj PawarAbhay SinghMukesh ShuklaBhola NathBackground & objectives: There is a persistent high microfilaria rate and variable reporting of coverage of Mass Drug Administration (MDA). This study aims to estimate the coverage, effective coverage, and compliance of drugs administered under MDA and determine the predictors affecting effective coverage. Methods: A community-based cross-sectional study was conducted in Amethi, Lucknow, Raebareli and Sultanpur districts of Uttar Pradesh, India. The study participants were selected using multi-stage random sampling using Probability Proportional to Estimated Size (PPES). The coverage, effective coverage and compliance of drugs were presented as proportion. The multivariable logistic regression model was applied to identify the significant predictors for effective coverage. Results: Of 4151 participants, 997 (24.0%), 340 (8.2%), 1158 (27.9%) and 1656 (39.9%) belonged to Amethi, Lucknow, Raebareli and Sultanpur districts, respectively. The coverage ranged from 49.8% to 87.9% and effective coverage ranged from 51.8% to 73.2% across districts. The compliance was the poorest (70.7%) in Sultanpur. The source of information about MDA, gender of the study participants and area of residence emerged as predictors for effective coverage in the districts. Interpretation & conclusion: The effective coverage was poor with good drug compliance across the districts. There is a need for a well-designed pre-MDA campaign addressing the fear of side effects of drugs and emphasizing the presence of the community during the MDA round along with monitoring and evaluation of the round.https://journals.lww.com/10.4103/JVBD.JVBD_102_24complianceeffective coverageendemiclymphatic filariasismass drug administration |
| spellingShingle | Sourabh Paul Aswani Kumar Seth Neeraj Pawar Abhay Singh Mukesh Shukla Bhola Nath Coverage and evaluation survey of post-mass drug administration for lymphatic filariasis in four endemic districts of Uttar Pradesh: Are we on the track? Journal of Vector Borne Diseases compliance effective coverage endemic lymphatic filariasis mass drug administration |
| title | Coverage and evaluation survey of post-mass drug administration for lymphatic filariasis in four endemic districts of Uttar Pradesh: Are we on the track? |
| title_full | Coverage and evaluation survey of post-mass drug administration for lymphatic filariasis in four endemic districts of Uttar Pradesh: Are we on the track? |
| title_fullStr | Coverage and evaluation survey of post-mass drug administration for lymphatic filariasis in four endemic districts of Uttar Pradesh: Are we on the track? |
| title_full_unstemmed | Coverage and evaluation survey of post-mass drug administration for lymphatic filariasis in four endemic districts of Uttar Pradesh: Are we on the track? |
| title_short | Coverage and evaluation survey of post-mass drug administration for lymphatic filariasis in four endemic districts of Uttar Pradesh: Are we on the track? |
| title_sort | coverage and evaluation survey of post mass drug administration for lymphatic filariasis in four endemic districts of uttar pradesh are we on the track |
| topic | compliance effective coverage endemic lymphatic filariasis mass drug administration |
| url | https://journals.lww.com/10.4103/JVBD.JVBD_102_24 |
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