Cobalamin deficiency and pathogenesis of neurological disorders

The brief review deals with the specific value of B vitamins for the nervous system, the mechanisms of transport and metabolic functions of cobalamin, pathogenetic theories related to vitamin B12 deficiency such as canonical biochemical theory and the theory of dysregulation of cytokines and growth...

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Main Authors: A. V. Pereshein, S. V. Kuznetsova, T. E. Potemina
Format: Article
Language:Russian
Published: Private institution educational organization of higher education "Medical University "ReaViz" 2021-12-01
Series:Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
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Online Access:https://vestnik.reaviz.ru/jour/article/view/343
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author A. V. Pereshein
S. V. Kuznetsova
T. E. Potemina
author_facet A. V. Pereshein
S. V. Kuznetsova
T. E. Potemina
author_sort A. V. Pereshein
collection DOAJ
description The brief review deals with the specific value of B vitamins for the nervous system, the mechanisms of transport and metabolic functions of cobalamin, pathogenetic theories related to vitamin B12 deficiency such as canonical biochemical theory and the theory of dysregulation of cytokines and growth factors; the hyperhomocysteinemic component of cerebral small vessel disease as one of the most common types of degenerative disorders of the central nervous system has been mentioned; the types of disorders associated with cobalamin deficiency that underlie its neurological manifestations have been described.
format Article
id doaj-art-28975b915ad54f1aa09c65fc95331d2c
institution Kabale University
issn 2226-762X
2782-1579
language Russian
publishDate 2021-12-01
publisher Private institution educational organization of higher education "Medical University "ReaViz"
record_format Article
series Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
spelling doaj-art-28975b915ad54f1aa09c65fc95331d2c2025-08-20T03:37:22ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792021-12-0106213210.20340/vmi-rvz.2021.6.PHYS.1275Cobalamin deficiency and pathogenesis of neurological disordersA. V. Pereshein0S. V. Kuznetsova1T. E. Potemina2Privolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityThe brief review deals with the specific value of B vitamins for the nervous system, the mechanisms of transport and metabolic functions of cobalamin, pathogenetic theories related to vitamin B12 deficiency such as canonical biochemical theory and the theory of dysregulation of cytokines and growth factors; the hyperhomocysteinemic component of cerebral small vessel disease as one of the most common types of degenerative disorders of the central nervous system has been mentioned; the types of disorders associated with cobalamin deficiency that underlie its neurological manifestations have been described.https://vestnik.reaviz.ru/jour/article/view/343cobalamindeficiencyneurodegenerationpathogenesisneurological manifestationshomocysteine
spellingShingle A. V. Pereshein
S. V. Kuznetsova
T. E. Potemina
Cobalamin deficiency and pathogenesis of neurological disorders
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
cobalamin
deficiency
neurodegeneration
pathogenesis
neurological manifestations
homocysteine
title Cobalamin deficiency and pathogenesis of neurological disorders
title_full Cobalamin deficiency and pathogenesis of neurological disorders
title_fullStr Cobalamin deficiency and pathogenesis of neurological disorders
title_full_unstemmed Cobalamin deficiency and pathogenesis of neurological disorders
title_short Cobalamin deficiency and pathogenesis of neurological disorders
title_sort cobalamin deficiency and pathogenesis of neurological disorders
topic cobalamin
deficiency
neurodegeneration
pathogenesis
neurological manifestations
homocysteine
url https://vestnik.reaviz.ru/jour/article/view/343
work_keys_str_mv AT avpereshein cobalamindeficiencyandpathogenesisofneurologicaldisorders
AT svkuznetsova cobalamindeficiencyandpathogenesisofneurologicaldisorders
AT tepotemina cobalamindeficiencyandpathogenesisofneurologicaldisorders