Efficacy of deep biopsy for subepithelial lesions in the upper gastrointestinal tract
Introduction : Accurate diagnosis of subepithelial lesions (SELs) in the gastrointestinal tract depends on a variety of methods: endoscopy, endoscopic ultrasound and different types of biopsy. Making an error-free diagnosis is vital for the subsequent application of an appropriate treatment. Aim:...
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Medycyna Praktyczna
2016-07-01
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| Series: | Videosurgery and Other Miniinvasive Techniques |
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| Online Access: | https://www.termedia.pl/Efficacy-of-deep-biopsy-for-subepithelial-lesions-in-the-upper-r-ngastrointestinal-tract,42,28044,1,1.html |
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| author | Rolandas Vaicekauskas Juozas Stanaitis Jonas Valantinas |
| author_facet | Rolandas Vaicekauskas Juozas Stanaitis Jonas Valantinas |
| author_sort | Rolandas Vaicekauskas |
| collection | DOAJ |
| description | Introduction : Accurate diagnosis of subepithelial lesions (SELs) in the gastrointestinal tract depends on a variety of methods: endoscopy, endoscopic ultrasound and different types of biopsy. Making an error-free diagnosis is vital for the subsequent application of an appropriate treatment.
Aim: To evaluate the efficacy of deep biopsy via the endoscopic submucosal dissection (ESD) technique for SELs in the upper gastrointestinal tract.
Material and methods: It was a case series study. Deep biopsy via the ESD technique was completed in 38 patients between November 2012 and October 2014. Thirty-eight SELs in the upper gastrointestinal tract of varying size (very small ≤ 1 cm, small 1–2 cm and large ≥ 2 cm) by means of the ESD technique after an incision with an electrosurgical knife of the overlying layers and revealing a small part of the lesion were biopsied under direct endoscopic view.
Results: Deep biopsy via the ESD technique was diagnostic in 28 of 38 patients (73.3%; 95% CI: 59.7–89.7%). The diagnostic yield for SELs with a clear endophytic shape increased to 91.3%. An evident endophytic appearance of a subepithelial lesion, the mean number of biopsied samples (6.65 ±1.36) and the total size in length of all samples per case (19.88 ±8.07 mm) were the main criteria influencing the positiveness of deep biopsy in the diagnostic group compared to the nondiagnostic one (p = 0.001; p = 0.025; p = 0.008).
Conclusions : Deep biopsy via the ESD technique is an effective and safe method for the diagnosis of SELs especially with a clear endophytic appearance in a large number of biopsied samples. |
| format | Article |
| id | doaj-art-28927fc109cf4e17bcd7604a9b60ffc7 |
| institution | DOAJ |
| issn | 1895-4588 2299-0054 |
| language | English |
| publishDate | 2016-07-01 |
| publisher | Medycyna Praktyczna |
| record_format | Article |
| series | Videosurgery and Other Miniinvasive Techniques |
| spelling | doaj-art-28927fc109cf4e17bcd7604a9b60ffc72025-08-20T03:17:47ZengMedycyna PraktycznaVideosurgery and Other Miniinvasive Techniques1895-45882299-00542016-07-0111319219910.5114/wiitm.2016.6142928044Efficacy of deep biopsy for subepithelial lesions in the upper gastrointestinal tractRolandas VaicekauskasJuozas StanaitisJonas ValantinasIntroduction : Accurate diagnosis of subepithelial lesions (SELs) in the gastrointestinal tract depends on a variety of methods: endoscopy, endoscopic ultrasound and different types of biopsy. Making an error-free diagnosis is vital for the subsequent application of an appropriate treatment. Aim: To evaluate the efficacy of deep biopsy via the endoscopic submucosal dissection (ESD) technique for SELs in the upper gastrointestinal tract. Material and methods: It was a case series study. Deep biopsy via the ESD technique was completed in 38 patients between November 2012 and October 2014. Thirty-eight SELs in the upper gastrointestinal tract of varying size (very small ≤ 1 cm, small 1–2 cm and large ≥ 2 cm) by means of the ESD technique after an incision with an electrosurgical knife of the overlying layers and revealing a small part of the lesion were biopsied under direct endoscopic view. Results: Deep biopsy via the ESD technique was diagnostic in 28 of 38 patients (73.3%; 95% CI: 59.7–89.7%). The diagnostic yield for SELs with a clear endophytic shape increased to 91.3%. An evident endophytic appearance of a subepithelial lesion, the mean number of biopsied samples (6.65 ±1.36) and the total size in length of all samples per case (19.88 ±8.07 mm) were the main criteria influencing the positiveness of deep biopsy in the diagnostic group compared to the nondiagnostic one (p = 0.001; p = 0.025; p = 0.008). Conclusions : Deep biopsy via the ESD technique is an effective and safe method for the diagnosis of SELs especially with a clear endophytic appearance in a large number of biopsied samples.https://www.termedia.pl/Efficacy-of-deep-biopsy-for-subepithelial-lesions-in-the-upper-r-ngastrointestinal-tract,42,28044,1,1.html<i>deep biopsy endoscopic submucosal dissection subepithelial lesions gastrointestinal stromal tumor</i> |
| spellingShingle | Rolandas Vaicekauskas Juozas Stanaitis Jonas Valantinas Efficacy of deep biopsy for subepithelial lesions in the upper gastrointestinal tract Videosurgery and Other Miniinvasive Techniques <i>deep biopsy endoscopic submucosal dissection subepithelial lesions gastrointestinal stromal tumor</i> |
| title | Efficacy of deep biopsy for subepithelial lesions in the upper
gastrointestinal tract |
| title_full | Efficacy of deep biopsy for subepithelial lesions in the upper
gastrointestinal tract |
| title_fullStr | Efficacy of deep biopsy for subepithelial lesions in the upper
gastrointestinal tract |
| title_full_unstemmed | Efficacy of deep biopsy for subepithelial lesions in the upper
gastrointestinal tract |
| title_short | Efficacy of deep biopsy for subepithelial lesions in the upper
gastrointestinal tract |
| title_sort | efficacy of deep biopsy for subepithelial lesions in the upper gastrointestinal tract |
| topic | <i>deep biopsy endoscopic submucosal dissection subepithelial lesions gastrointestinal stromal tumor</i> |
| url | https://www.termedia.pl/Efficacy-of-deep-biopsy-for-subepithelial-lesions-in-the-upper-r-ngastrointestinal-tract,42,28044,1,1.html |
| work_keys_str_mv | AT rolandasvaicekauskas efficacyofdeepbiopsyforsubepitheliallesionsintheuppergastrointestinaltract AT juozasstanaitis efficacyofdeepbiopsyforsubepitheliallesionsintheuppergastrointestinaltract AT jonasvalantinas efficacyofdeepbiopsyforsubepitheliallesionsintheuppergastrointestinaltract |