LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROL

The literary review presents an analysis of modern views of the biomechanical properties of lamina cribrosa (LC) in glaucoma. It is shown that LC deformations in glaucomatous eyes are connected with their morphological and structural disorders at macro- and micro levels even in the early stages of g...

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Main Authors: O. A. Kiseleva, E. N. Iomdina, L. V. Yakubova, D. D. Khoziev
Format: Article
Language:Russian
Published: Real Time Ltd 2018-10-01
Series:Российский офтальмологический журнал
Subjects:
Online Access:https://roj.igb.ru/jour/article/view/174
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author O. A. Kiseleva
E. N. Iomdina
L. V. Yakubova
D. D. Khoziev
author_facet O. A. Kiseleva
E. N. Iomdina
L. V. Yakubova
D. D. Khoziev
author_sort O. A. Kiseleva
collection DOAJ
description The literary review presents an analysis of modern views of the biomechanical properties of lamina cribrosa (LC) in glaucoma. It is shown that LC deformations in glaucomatous eyes are connected with their morphological and structural disorders at macro- and micro levels even in the early stages of glaucoma development. New visualization technologies of ocular structures, in particular, optical coherent tomography with enhanced depth imaging (EDI) enable in vivo evaluation of biomechanical characteristics of LC and its stress-strain from the data on the changing shape of its anterior surface (curvature index), thickness and deepness, pore dimensions, presence and severity of LC tissue defects. LC changes inherent to glaucoma are significant criteria for the estimation of the risk of glaucoma emergence and its early diagnostics, determination of the stage of the pathological process, and prediction of its progression rate. For citation: Kiseleva O.A., Iomdina E.N., Yakubova L.V., Khoziev D.D. Lamina cribrosa in glaucoma: biomechanical properties and possibilities of their clinical control. Russian ophthalmological journal. 2018; 11 (3):76-83 (In Russian). doi: 10.21516/2072-0076-2018-11-3-76-83
format Article
id doaj-art-28926b2b08ed4ee784f9a28a133f3d1e
institution Kabale University
issn 2072-0076
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language Russian
publishDate 2018-10-01
publisher Real Time Ltd
record_format Article
series Российский офтальмологический журнал
spelling doaj-art-28926b2b08ed4ee784f9a28a133f3d1e2025-08-20T03:40:11ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602018-10-01113768310.21516/2072-0076-2018-11-3-76-83174LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROLO. A. Kiseleva0E. N. Iomdina1L. V. Yakubova2D. D. Khoziev3Moscow Helmholtz Research Institute of Eye DiseasesMoscow Helmholtz Research Institute of Eye DiseasesMoscow Helmholtz Research Institute of Eye DiseasesMoscow Helmholtz Research Institute of Eye DiseasesThe literary review presents an analysis of modern views of the biomechanical properties of lamina cribrosa (LC) in glaucoma. It is shown that LC deformations in glaucomatous eyes are connected with their morphological and structural disorders at macro- and micro levels even in the early stages of glaucoma development. New visualization technologies of ocular structures, in particular, optical coherent tomography with enhanced depth imaging (EDI) enable in vivo evaluation of biomechanical characteristics of LC and its stress-strain from the data on the changing shape of its anterior surface (curvature index), thickness and deepness, pore dimensions, presence and severity of LC tissue defects. LC changes inherent to glaucoma are significant criteria for the estimation of the risk of glaucoma emergence and its early diagnostics, determination of the stage of the pathological process, and prediction of its progression rate. For citation: Kiseleva O.A., Iomdina E.N., Yakubova L.V., Khoziev D.D. Lamina cribrosa in glaucoma: biomechanical properties and possibilities of their clinical control. Russian ophthalmological journal. 2018; 11 (3):76-83 (In Russian). doi: 10.21516/2072-0076-2018-11-3-76-83https://roj.igb.ru/jour/article/view/174первичная открытоугольная глаукомарешетчатая пластинка склерыдеформацияоптическая когерентная томографияprimary open angle glaucomalamina cribrosadeformationoptical coherent tomography
spellingShingle O. A. Kiseleva
E. N. Iomdina
L. V. Yakubova
D. D. Khoziev
LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROL
Российский офтальмологический журнал
первичная открытоугольная глаукома
решетчатая пластинка склеры
деформация
оптическая когерентная томография
primary open angle glaucoma
lamina cribrosa
deformation
optical coherent tomography
title LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROL
title_full LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROL
title_fullStr LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROL
title_full_unstemmed LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROL
title_short LAMINA CRIBROSA IN GLAUCOMA: BIOMECHANICAL PROPERTIES AND POSSIBILITIES OF THEIR CLINICAL CONTROL
title_sort lamina cribrosa in glaucoma biomechanical properties and possibilities of their clinical control
topic первичная открытоугольная глаукома
решетчатая пластинка склеры
деформация
оптическая когерентная томография
primary open angle glaucoma
lamina cribrosa
deformation
optical coherent tomography
url https://roj.igb.ru/jour/article/view/174
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AT eniomdina laminacribrosainglaucomabiomechanicalpropertiesandpossibilitiesoftheirclinicalcontrol
AT lvyakubova laminacribrosainglaucomabiomechanicalpropertiesandpossibilitiesoftheirclinicalcontrol
AT ddkhoziev laminacribrosainglaucomabiomechanicalpropertiesandpossibilitiesoftheirclinicalcontrol