Exploring and expanding the natural chemical space of bacterial diterpenes

Exploring and expanding the natural chemical space of bacterial diterpenes

Abstract Terpenoids are the largest family of natural products but relatively rare in bacteria. Genome mining reveals widespread prevalence of terpene synthases, the enzymes responsible for constructing the hydrocarbon skeletons, in bacteria. Here, we show that 125 (37%) of 334 terpene synthases fro...

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Bibliographic Details
Main Authors: Xiuting Wei, Wenbo Ning, Caitlin A. McCadden, Tyler A. Alsup, Zining Li, Diana P. Łomowska-Keehner, Jordan Nafie, Tracy Qu, Melvin Osei Opoku, Glen R. Gillia, Baofu Xu, Daniel G. Icenhour, Jeffrey D. Rudolf
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57145-6
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