Behavioral phenotyping identifies autism-like repetitive stereotypies in a Tsc2 haploinsufficient rat model

Behavioral phenotyping identifies autism-like repetitive stereotypies in a Tsc2 haploinsufficient rat model

Abstract Besides deficits in social communication and interaction, repetitive behavior patterns are core manifestations of autism spectrum disorder (ASD). Phenotypes are heterogeneous and can range from simple lower-order motor stereotypies to more complex higher-order cognitive inflexibility and fi...

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Main Authors: Antonia Ramme, Mirjam Zachow, Bettina Habelt, Iveta Vojtechova, Tomas Petrasek, Robert Waltereit, Nadine Bernhardt
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Behavioral and Brain Functions
Subjects:
Autism spectrum disorder
Tuberous sclerosis complex
Repetitive behavior
Eker rat
Online Access:https://doi.org/10.1186/s12993-025-00284-z
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https://doi.org/10.1186/s12993-025-00284-z

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