Taste Masking Techniques of Unpleasant Drugs
Background: Taste masking is one of the many processes that are used in the pharmaceutical industry. This is done with the intention masking or decreasing of a disagreeable taste or odor from the organic compounds which are usually used in the oral cavity and can be formulated by several types of t...
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College of Medicine University of Baghdad
2025-07-01
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| Series: | مجلة كلية الطب |
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| Online Access: | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2164 |
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| author | Hiba M. Suza Eman B. Hazim |
| author_facet | Hiba M. Suza Eman B. Hazim |
| author_sort | Hiba M. Suza |
| collection | DOAJ |
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Background: Taste masking is one of the many processes that are used in the pharmaceutical industry. This is done with the intention masking or decreasing of a disagreeable taste or odor from the organic compounds which are usually used in the oral cavity and can be formulated by several types of techniques.
Objective: To highlight the definition and importance of taste masking, the factors that affect taste masking, the many types of taste masking techniques that can be used, and the evaluation of taste masking in vitro and in vivo evaluations.
Results: The masking of unpleasant taste or odor is important in the marketed product to improve patients’ compliance, especially for pediatric and geriatric patients, because it is necessary for the improvement of the therapeutic efficacy, and that’s can be obtained by several methods of taste-masking techniques; furthermore, these techniques may be simple, namely, like adding a sweetener or flavored agents, or by using other complicated methods like polymer coating, complexation, resin ionic exchange, external or internal ionic gelation, physical or chemical adsorption, granulation, microencapsulation, solid dispersion, effervescence, viscosity modification, nanosuspension, pro-drug and so on; it sometimes needs the combination of more than two methods to overcome very bad taste, and depends on the severity of the undesirable taste.
Conclusion: The undesirable taste or odor can be masked by using different types of techniques depending on the intensity of the bad taste or odor, in addition to other factors that are related to the drug itself and the method of the dosage form that was chosen, and other factors. Taste masking was needed to improve patients’ compliance with the marketed products, and that is an important factor to ensure total completion of the drug course by patients.
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| format | Article |
| id | doaj-art-287a1e31175f4ceb97feb8abd2b228d2 |
| institution | OA Journals |
| issn | 0041-9419 2410-8057 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | College of Medicine University of Baghdad |
| record_format | Article |
| series | مجلة كلية الطب |
| spelling | doaj-art-287a1e31175f4ceb97feb8abd2b228d22025-08-20T02:38:02ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572025-07-0167No. 210.32007/jfacmedbaghdad2164Taste Masking Techniques of Unpleasant DrugsHiba M. Suza0https://orcid.org/0009-0009-2187-3808Eman B. Hazim1https://orcid.org/0000-0002-6316-4155Department of Pharmaceutics, College of Pharmacy, University of Baghdad, Baghdad, Iraq.Department of Pharmaceutics, College of Pharmacy, University of Baghdad, Baghdad, Iraq. Background: Taste masking is one of the many processes that are used in the pharmaceutical industry. This is done with the intention masking or decreasing of a disagreeable taste or odor from the organic compounds which are usually used in the oral cavity and can be formulated by several types of techniques. Objective: To highlight the definition and importance of taste masking, the factors that affect taste masking, the many types of taste masking techniques that can be used, and the evaluation of taste masking in vitro and in vivo evaluations. Results: The masking of unpleasant taste or odor is important in the marketed product to improve patients’ compliance, especially for pediatric and geriatric patients, because it is necessary for the improvement of the therapeutic efficacy, and that’s can be obtained by several methods of taste-masking techniques; furthermore, these techniques may be simple, namely, like adding a sweetener or flavored agents, or by using other complicated methods like polymer coating, complexation, resin ionic exchange, external or internal ionic gelation, physical or chemical adsorption, granulation, microencapsulation, solid dispersion, effervescence, viscosity modification, nanosuspension, pro-drug and so on; it sometimes needs the combination of more than two methods to overcome very bad taste, and depends on the severity of the undesirable taste. Conclusion: The undesirable taste or odor can be masked by using different types of techniques depending on the intensity of the bad taste or odor, in addition to other factors that are related to the drug itself and the method of the dosage form that was chosen, and other factors. Taste masking was needed to improve patients’ compliance with the marketed products, and that is an important factor to ensure total completion of the drug course by patients. https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2164Bitter tastePatients’ complianceTaste budsTaste maskingUnpleasant taste |
| spellingShingle | Hiba M. Suza Eman B. Hazim Taste Masking Techniques of Unpleasant Drugs مجلة كلية الطب Bitter taste Patients’ compliance Taste buds Taste masking Unpleasant taste |
| title | Taste Masking Techniques of Unpleasant Drugs |
| title_full | Taste Masking Techniques of Unpleasant Drugs |
| title_fullStr | Taste Masking Techniques of Unpleasant Drugs |
| title_full_unstemmed | Taste Masking Techniques of Unpleasant Drugs |
| title_short | Taste Masking Techniques of Unpleasant Drugs |
| title_sort | taste masking techniques of unpleasant drugs |
| topic | Bitter taste Patients’ compliance Taste buds Taste masking Unpleasant taste |
| url | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2164 |
| work_keys_str_mv | AT hibamsuza tastemaskingtechniquesofunpleasantdrugs AT emanbhazim tastemaskingtechniquesofunpleasantdrugs |