Synthesis of Rhodamine TEMPO Conjugates via Isonitrile‐Based Multicomponent‐Reactions for Mitochondria‐Targeted ROS‐Detection in Cancer Cells

Synthesis of Rhodamine TEMPO Conjugates via Isonitrile‐Based Multicomponent‐Reactions for Mitochondria‐Targeted ROS‐Detection in Cancer Cells

Abstract A novel series of profluorescent rhodamine nitroxide conjugates are synthesized utilizing well‐known isonitrile‐based multicomponent reactions (IMCRs). The synthesized conjugates are rationally designed as mitochondria‐targeting probes for the detection of reactive oxygen species in living...

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Bibliographic Details
Main Authors: Haider N. Sultani, Ibrahim M. Morgan, Hidayat Hussain, Haleh H. Haeri, Dariush Hinderberger, Goran N. Kaluđerović, Bernhard Westermann
Format: Article
Language:English
Published: Wiley-VCH 2025-05-01
Series:Advanced Sensor Research
Subjects:
bioimaging
EPR
mitochondria‐targeting sensors
multicomponent reactions (MCRs)
rhodamine TEMPO conjugates
ROS detection
Online Access:https://doi.org/10.1002/adsr.202400180
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