Evolutionary adaptation of probiotics in the gut: selection pressures, optimization strategies, and regulatory challenges

Abstract Probiotics and live bacterial therapeutics are garnering increased attention for use in human health and have the potential to revolutionise the treatment of gastrointestinal diseases. However, a pervasive feature of bacteria that must be considered in the design of safe and effective probi...

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Bibliographic Details
Main Authors: Julia Leeflang, Josephine A. Wright, Daniel L. Worthley, M. Omar Din, Susan L. Woods
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-025-00734-6
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