Helicobacter pylori Infection and Anemia in Taiwanese Adults
Background. Chronic Helicobacter pylori infection and iron-deficiency anemia (IDA) are common in adults. Although the most common causes of IDA usually arise from the gastrointestinal tract, the association between chronic Helicobacter pylori infection and anemia remains unclear. Aim. To evaluate th...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2013/390967 |
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| author | Hsiang-Yao Shih Fu-Chen Kuo Sophie S. W. Wang Yi-Chang Liu Meng-Chieh Wu Yang-Pei Chang Guei-Fen Chiu Pi-Yu Chang Deng-Chyang Wu Ming-Chia Hsieh Yao-Li Chen |
| author_facet | Hsiang-Yao Shih Fu-Chen Kuo Sophie S. W. Wang Yi-Chang Liu Meng-Chieh Wu Yang-Pei Chang Guei-Fen Chiu Pi-Yu Chang Deng-Chyang Wu Ming-Chia Hsieh Yao-Li Chen |
| author_sort | Hsiang-Yao Shih |
| collection | DOAJ |
| description | Background. Chronic Helicobacter pylori infection and iron-deficiency anemia (IDA) are common in adults. Although the most common causes of IDA usually arise from the gastrointestinal tract, the association between chronic Helicobacter pylori infection and anemia remains unclear. Aim. To evaluate the association of chronic Helicobacter pylori infection and IDA. Materials and Methods. We enrolled 882 patients from January 2010 to April 2013. The status of Helicobacter pylori (H.p) infection was confirmed and blood samples from the same participants were taken on the same day to check the level of hemoglobin, serum iron, ferritin, and total iron-binding capacity (TIBC). Results. No significant difference was noted from the demographic data. The average level of hemoglobin (Hb) was not different between negative and positive groups, pos 13.57 g/dL versus neg 13.65 g/dL (P=0.699). Although the levels of serum IDA related parameters were expected in positive group (lower serum iron and ferritin and higher TIBC) these differences did not reach statistical significance (P=0.824 for iron, P=0.360 for ferritin, and P=0.252 for TIBC). Conclusion. Chronic Helicobacter pylori infection is not attributed to IDA. The levels of hemoglobin, serum iron and ferritin, and TIBC remain unaffected after chronic H.p infection. Large-scale clinical studies are needed to prove the association. |
| format | Article |
| id | doaj-art-2873a364c76243d09729062aa49500bb |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-2873a364c76243d09729062aa49500bb2025-02-03T01:01:05ZengWileyGastroenterology Research and Practice1687-61211687-630X2013-01-01201310.1155/2013/390967390967Helicobacter pylori Infection and Anemia in Taiwanese AdultsHsiang-Yao Shih0Fu-Chen Kuo1Sophie S. W. Wang2Yi-Chang Liu3Meng-Chieh Wu4Yang-Pei Chang5Guei-Fen Chiu6Pi-Yu Chang7Deng-Chyang Wu8Ming-Chia Hsieh9Yao-Li Chen10Department of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung City 812, TaiwanSchool of Medicine, College of Medicine, I-Shou University and E-Da Hospital, Kaohsiung City 824, TaiwanDivision of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung City 807, TaiwanDivision of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung City 807, TaiwanDepartment of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung City 812, TaiwanDepartment of Neurology, Kaohsiung Medical University Hospital, Kaohsiung City 807, TaiwanDepartment of Information, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung City 801, TaiwanAdministration Center, Kaohsiung Medical University Hospital, Kaohsiung City 807, TaiwanDepartment of Internal Medicine, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung City 812, TaiwanDivision of Endocrinology and Metabolism, Department of Internal Medicine, Changhua Christian Hospital, Changhua County 500, TaiwanDepartment of General Surgery, Changhua Christian Hospital, Changhua County 500, TaiwanBackground. Chronic Helicobacter pylori infection and iron-deficiency anemia (IDA) are common in adults. Although the most common causes of IDA usually arise from the gastrointestinal tract, the association between chronic Helicobacter pylori infection and anemia remains unclear. Aim. To evaluate the association of chronic Helicobacter pylori infection and IDA. Materials and Methods. We enrolled 882 patients from January 2010 to April 2013. The status of Helicobacter pylori (H.p) infection was confirmed and blood samples from the same participants were taken on the same day to check the level of hemoglobin, serum iron, ferritin, and total iron-binding capacity (TIBC). Results. No significant difference was noted from the demographic data. The average level of hemoglobin (Hb) was not different between negative and positive groups, pos 13.57 g/dL versus neg 13.65 g/dL (P=0.699). Although the levels of serum IDA related parameters were expected in positive group (lower serum iron and ferritin and higher TIBC) these differences did not reach statistical significance (P=0.824 for iron, P=0.360 for ferritin, and P=0.252 for TIBC). Conclusion. Chronic Helicobacter pylori infection is not attributed to IDA. The levels of hemoglobin, serum iron and ferritin, and TIBC remain unaffected after chronic H.p infection. Large-scale clinical studies are needed to prove the association.http://dx.doi.org/10.1155/2013/390967 |
| spellingShingle | Hsiang-Yao Shih Fu-Chen Kuo Sophie S. W. Wang Yi-Chang Liu Meng-Chieh Wu Yang-Pei Chang Guei-Fen Chiu Pi-Yu Chang Deng-Chyang Wu Ming-Chia Hsieh Yao-Li Chen Helicobacter pylori Infection and Anemia in Taiwanese Adults Gastroenterology Research and Practice |
| title | Helicobacter pylori Infection and Anemia in Taiwanese Adults |
| title_full | Helicobacter pylori Infection and Anemia in Taiwanese Adults |
| title_fullStr | Helicobacter pylori Infection and Anemia in Taiwanese Adults |
| title_full_unstemmed | Helicobacter pylori Infection and Anemia in Taiwanese Adults |
| title_short | Helicobacter pylori Infection and Anemia in Taiwanese Adults |
| title_sort | helicobacter pylori infection and anemia in taiwanese adults |
| url | http://dx.doi.org/10.1155/2013/390967 |
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