Single cell RNA sequencing to identify an Immunogenic cell death related prognostic signature in intrahepatic cholangiocarcinoma

Single cell RNA sequencing to identify an Immunogenic cell death related prognostic signature in intrahepatic cholangiocarcinoma

Abstract Immunogenic cell death (ICD) is crucial for cancer development and enhances the effectiveness of immunotherapy by triggering an adaptive immune response. However, the impact of ICD-related genes (ICDRGs) on iCCA progression and patient prognosis remains unclear. iCCA samples from The Cancer...

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Bibliographic Details
Main Authors: Bowen Sha, Fei Tong, Qinghua Shu, Miao Wu, Liang Zhao, Yufeng Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Immunogenic cell death
Intrahepatic cholangiocarcinoma
Tumor microenvironment
Prognostic biomarker
Single-cell RNA sequencing
Online Access:https://doi.org/10.1038/s41598-025-08602-1
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