Personalized use of ketamine and esketamine for treatment-resistant depression

Personalized use of ketamine and esketamine for treatment-resistant depression

Abstract A large and disproportionate portion of the burden associated with major depressive disorder (MDD) is due to treatment-resistant depression (TRD). Intravenous (R,S)-ketamine (ketamine) and intranasal (S)-ketamine (esketamine) are rapid-acting antidepressants that can effectively treat TRD....

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Bibliographic Details
Main Authors: Gustavo C. Medeiros, Isabella Demo, Fernando S. Goes, Carlos A. Zarate, Todd D. Gould
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-03180-8
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