Visualizing androgen signaling and assessing its interaction with canonical Wnt signaling pathways in prostate development, morphogenesis, and regeneration.

The androgen receptor (AR) is a nuclear hormone receptor, and its activation through binding to androgens is essential for prostate development, morphogenesis, growth, and tumorigenesis. Although significant efforts have been devoted to understanding the critical role of AR, the cellular properties...

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Main Authors: Yao Mawulikplimi Adzavon, Dong-Hoon Lee, Alex Hiroto, Tae Ju Park, Gaeul Chu, Yunjeong Kim, Kristoffer Nikias, Cheong-Wun Kim, Dexter Hoi Long Leung, Chenmiao Liu, Hong Zeng, Zijie Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011756
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