Aristides Leão: a birth centennial homage with comments on his spreading depression
The year of 2014 is the birth centenary of Aristides Azevedo Pacheco Leão (1914-1993), and also marks seventy years of the publication of his discovery of the novel electrophysiological phenomenon, named by him “spreading depression” (SD), soon designated “Leão’s wave” or “Leão’s spreading depressio...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
2015-06-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000600544&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849701190269403136 |
|---|---|
| author | Eliasz Engelhardt Marleide da Mota Gomes |
| author_facet | Eliasz Engelhardt Marleide da Mota Gomes |
| author_sort | Eliasz Engelhardt |
| collection | DOAJ |
| description | The year of 2014 is the birth centenary of Aristides Azevedo Pacheco Leão (1914-1993), and also marks seventy years of the publication of his discovery of the novel electrophysiological phenomenon, named by him “spreading depression” (SD), soon designated “Leão’s wave” or “Leão’s spreading depression”. This was a remarkable scientific milestone, and the author must be celebrated for this achievement, as the studies he triggered proceeded worldwide, with new concepts, as spreading depolarization, until the present days. Robust experimental and clinical evidence emerged to suggest that these and related electrophysiological phenomena are involved in the mechanisms of migraine aura, acute cerebrovascular diseases, traumatic brain injury, transient global amnesia, epileptic seizures, and their pathophysiological characteristics come to offer new therapeutic perspectives. He was a remarkable and complex personality, and the authors remit the readers to a paper where his personal life is contemplated. |
| format | Article |
| id | doaj-art-284cc43e35f74c06a5fc27deeb15a050 |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 2015-06-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-284cc43e35f74c06a5fc27deeb15a0502025-08-20T03:18:01ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272015-06-0173654454610.1590/0004-282X20150045S0004-282X2015000600544Aristides Leão: a birth centennial homage with comments on his spreading depressionEliasz EngelhardtMarleide da Mota GomesThe year of 2014 is the birth centenary of Aristides Azevedo Pacheco Leão (1914-1993), and also marks seventy years of the publication of his discovery of the novel electrophysiological phenomenon, named by him “spreading depression” (SD), soon designated “Leão’s wave” or “Leão’s spreading depression”. This was a remarkable scientific milestone, and the author must be celebrated for this achievement, as the studies he triggered proceeded worldwide, with new concepts, as spreading depolarization, until the present days. Robust experimental and clinical evidence emerged to suggest that these and related electrophysiological phenomena are involved in the mechanisms of migraine aura, acute cerebrovascular diseases, traumatic brain injury, transient global amnesia, epileptic seizures, and their pathophysiological characteristics come to offer new therapeutic perspectives. He was a remarkable and complex personality, and the authors remit the readers to a paper where his personal life is contemplated.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000600544&lng=en&tlng=enAristides Leãoneurofisiologiadepressão alastranteenxaquecadoenças cerebrovascularesepilepsia |
| spellingShingle | Eliasz Engelhardt Marleide da Mota Gomes Aristides Leão: a birth centennial homage with comments on his spreading depression Arquivos de Neuro-Psiquiatria Aristides Leão neurofisiologia depressão alastrante enxaqueca doenças cerebrovasculares epilepsia |
| title | Aristides Leão: a birth centennial homage with comments on his spreading depression |
| title_full | Aristides Leão: a birth centennial homage with comments on his spreading depression |
| title_fullStr | Aristides Leão: a birth centennial homage with comments on his spreading depression |
| title_full_unstemmed | Aristides Leão: a birth centennial homage with comments on his spreading depression |
| title_short | Aristides Leão: a birth centennial homage with comments on his spreading depression |
| title_sort | aristides leao a birth centennial homage with comments on his spreading depression |
| topic | Aristides Leão neurofisiologia depressão alastrante enxaqueca doenças cerebrovasculares epilepsia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000600544&lng=en&tlng=en |
| work_keys_str_mv | AT eliaszengelhardt aristidesleaoabirthcentennialhomagewithcommentsonhisspreadingdepression AT marleidedamotagomes aristidesleaoabirthcentennialhomagewithcommentsonhisspreadingdepression |