Endometrial Receptivity–Lessons from “Omics”
The window of implantation (WOI) is a critical phase of the menstrual cycle during which the endometrial lining becomes receptive and facilitates embryo implantation. Drawing on findings from various branches of “omics”, including genomics, epigenomics, transcriptomics, proteomics, lipidomics, metab...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/15/1/106 |
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| author | Louie Ye Evdokia Dimitriadis |
| author_facet | Louie Ye Evdokia Dimitriadis |
| author_sort | Louie Ye |
| collection | DOAJ |
| description | The window of implantation (WOI) is a critical phase of the menstrual cycle during which the endometrial lining becomes receptive and facilitates embryo implantation. Drawing on findings from various branches of “omics”, including genomics, epigenomics, transcriptomics, proteomics, lipidomics, metabolomics, and microbiomics, this narrative review aims to (1) discuss mechanistic insights on endometrial receptivity and its implication in infertility; (2) highlight advances in investigations for endometrial receptivity; and (3) discuss novel diagnostic and therapeutic strategies that may improve reproductive outcomes. |
| format | Article |
| id | doaj-art-283edaea27d4408987acb3dc1b416705 |
| institution | Kabale University |
| issn | 2218-273X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj-art-283edaea27d4408987acb3dc1b4167052025-01-24T13:25:12ZengMDPI AGBiomolecules2218-273X2025-01-0115110610.3390/biom15010106Endometrial Receptivity–Lessons from “Omics”Louie Ye0Evdokia Dimitriadis1Reproductive Service Unit, The Royal Women’s Hospital, Melbourne, VIC 3052, AustraliaDepartment of Obstetrics, Gynaecology and Newborn Health, University of Melbourne, Melbourne, VIC 3052, AustraliaThe window of implantation (WOI) is a critical phase of the menstrual cycle during which the endometrial lining becomes receptive and facilitates embryo implantation. Drawing on findings from various branches of “omics”, including genomics, epigenomics, transcriptomics, proteomics, lipidomics, metabolomics, and microbiomics, this narrative review aims to (1) discuss mechanistic insights on endometrial receptivity and its implication in infertility; (2) highlight advances in investigations for endometrial receptivity; and (3) discuss novel diagnostic and therapeutic strategies that may improve reproductive outcomes.https://www.mdpi.com/2218-273X/15/1/106endometrial receptivityimplantationgenomicsepigenomicstranscriptomicsproteomics |
| spellingShingle | Louie Ye Evdokia Dimitriadis Endometrial Receptivity–Lessons from “Omics” Biomolecules endometrial receptivity implantation genomics epigenomics transcriptomics proteomics |
| title | Endometrial Receptivity–Lessons from “Omics” |
| title_full | Endometrial Receptivity–Lessons from “Omics” |
| title_fullStr | Endometrial Receptivity–Lessons from “Omics” |
| title_full_unstemmed | Endometrial Receptivity–Lessons from “Omics” |
| title_short | Endometrial Receptivity–Lessons from “Omics” |
| title_sort | endometrial receptivity lessons from omics |
| topic | endometrial receptivity implantation genomics epigenomics transcriptomics proteomics |
| url | https://www.mdpi.com/2218-273X/15/1/106 |
| work_keys_str_mv | AT louieye endometrialreceptivitylessonsfromomics AT evdokiadimitriadis endometrialreceptivitylessonsfromomics |