Calorie restriction increases muscle mitochondrial biogenesis in healthy humans.
<h4>Background</h4>Caloric restriction without malnutrition extends life span in a range of organisms including insects and mammals and lowers free radical production by the mitochondria. However, the mechanism responsible for this adaptation are poorly understood.<h4>Methods and f...
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| Main Authors: | Anthony E Civitarese, Stacy Carling, Leonie K Heilbronn, Mathew H Hulver, Barbara Ukropcova, Walter A Deutsch, Steven R Smith, Eric Ravussin, CALERIE Pennington Team |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-03-01
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| Series: | PLoS Medicine |
| Online Access: | https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0040076&type=printable |
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