Inconclusive Syphilis Results: A Retrospective Review of Public Health Results

In the context of increasing syphilis incidence in many Western countries, we sought to better understand the frequency and outcomes associated with inconclusive serologic syphilis results. To accomplish this, we reviewed all inconclusive results that arose from an indeterminant confirmatory trepone...

Full description

Saved in:
Bibliographic Details
Main Authors: Patrick O’Byrne, Leslie Tilley, Dara Spatz Friedman, Lauren Orser
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2020/5642952
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849307603540115456
author Patrick O’Byrne
Leslie Tilley
Dara Spatz Friedman
Lauren Orser
author_facet Patrick O’Byrne
Leslie Tilley
Dara Spatz Friedman
Lauren Orser
author_sort Patrick O’Byrne
collection DOAJ
description In the context of increasing syphilis incidence in many Western countries, we sought to better understand the frequency and outcomes associated with inconclusive serologic syphilis results. To accomplish this, we reviewed all inconclusive results that arose from an indeterminant confirmatory treponemal screen (specifically the Treponema pallidum particulate agglutination test), which were reported to Ottawa Public Health from January 1, 2019, through December 31, 2019. Our case review identified that 52 persons generated such test results during the study period, of whom 44.4% were cases requiring treatment, 46.3% were persons without new risk factors or symptoms of syphilis who had been previously treated for this infection, and 9.3% were not syphilis. Overall, these untreated syphilis cases accounted for 8.6% of all new syphilis diagnoses in our local jurisdiction during the study period. These results highlight that case investigation and prompt management of inconclusive syphilis results is an appropriate public health and clinical approach and that such a strategy could contribute to efforts to reduce increasing syphilis incidence.
format Article
id doaj-art-2834732f9b024be39016af98ff0ba062
institution Kabale University
issn 1712-9532
1918-1493
language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-2834732f9b024be39016af98ff0ba0622025-08-20T03:54:42ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932020-01-01202010.1155/2020/56429525642952Inconclusive Syphilis Results: A Retrospective Review of Public Health ResultsPatrick O’Byrne0Leslie Tilley1Dara Spatz Friedman2Lauren Orser3University of Ottawa, School of Nursing, 451 Smyth Road, Ottawa, Ontario K1H 8M5, CanadaOttawa Public Health, Infectious Diseases and Sexual Health Services, Ottawa, CanadaOttawa Public Health, Ottawa, CanadaOttawa Public Health, Infectious Diseases and Sexual Health Services, Ottawa, CanadaIn the context of increasing syphilis incidence in many Western countries, we sought to better understand the frequency and outcomes associated with inconclusive serologic syphilis results. To accomplish this, we reviewed all inconclusive results that arose from an indeterminant confirmatory treponemal screen (specifically the Treponema pallidum particulate agglutination test), which were reported to Ottawa Public Health from January 1, 2019, through December 31, 2019. Our case review identified that 52 persons generated such test results during the study period, of whom 44.4% were cases requiring treatment, 46.3% were persons without new risk factors or symptoms of syphilis who had been previously treated for this infection, and 9.3% were not syphilis. Overall, these untreated syphilis cases accounted for 8.6% of all new syphilis diagnoses in our local jurisdiction during the study period. These results highlight that case investigation and prompt management of inconclusive syphilis results is an appropriate public health and clinical approach and that such a strategy could contribute to efforts to reduce increasing syphilis incidence.http://dx.doi.org/10.1155/2020/5642952
spellingShingle Patrick O’Byrne
Leslie Tilley
Dara Spatz Friedman
Lauren Orser
Inconclusive Syphilis Results: A Retrospective Review of Public Health Results
Canadian Journal of Infectious Diseases and Medical Microbiology
title Inconclusive Syphilis Results: A Retrospective Review of Public Health Results
title_full Inconclusive Syphilis Results: A Retrospective Review of Public Health Results
title_fullStr Inconclusive Syphilis Results: A Retrospective Review of Public Health Results
title_full_unstemmed Inconclusive Syphilis Results: A Retrospective Review of Public Health Results
title_short Inconclusive Syphilis Results: A Retrospective Review of Public Health Results
title_sort inconclusive syphilis results a retrospective review of public health results
url http://dx.doi.org/10.1155/2020/5642952
work_keys_str_mv AT patrickobyrne inconclusivesyphilisresultsaretrospectivereviewofpublichealthresults
AT leslietilley inconclusivesyphilisresultsaretrospectivereviewofpublichealthresults
AT daraspatzfriedman inconclusivesyphilisresultsaretrospectivereviewofpublichealthresults
AT laurenorser inconclusivesyphilisresultsaretrospectivereviewofpublichealthresults