Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D
<i>Background and Objectives</i>: Chronic wounds severely impair patients’ quality of life (QoL), impacting physical, emotional, and functional well-being. Understanding the multidimensional effects of treatment is key to implementing effective, patient-centered care strategies. This stu...
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MDPI AG
2025-05-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/61/5/907 |
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| author | David Palomar-Albert Jorge Zamora-Ortiz Federico Palomar-Llatas Marta Escudero-Martínez Alba Naranjo-Cuellar Maria Isabel Pastor-Orduña |
| author_facet | David Palomar-Albert Jorge Zamora-Ortiz Federico Palomar-Llatas Marta Escudero-Martínez Alba Naranjo-Cuellar Maria Isabel Pastor-Orduña |
| author_sort | David Palomar-Albert |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Chronic wounds severely impair patients’ quality of life (QoL), impacting physical, emotional, and functional well-being. Understanding the multidimensional effects of treatment is key to implementing effective, patient-centered care strategies. This study aimed to assess changes in QoL among patients with chronic wounds using the Dermatology Life Quality Index (DLQI) and EuroQol-5D (EQ-5D), comparing outcomes across treatment modalities. <i>Materials and Methods</i>: A longitudinal observational study was conducted between 2019 and 2024 across three hospitals in the Valencian Community. A total of 278 patients with venous lower-limb ulcers of more than six weeks’ duration were included. Quality-of-life assessments were performed at baseline, one-month follow-up, and discharge. Treatments included alginate, foam, moist wound healing (MWH), compression therapy, and negative-pressure wound therapy (NPWT). Statistical analysis involved Friedman’s test and repeated-measures ANOVA. <i>Results</i>: Significant improvements were observed in overall QoL across most treatment modalities. EQ-5D scores progressively increased, while DLQI scores decreased. Pain, embarrassment, and limitations in daily life (e.g., shopping and social activities) showed marked reductions. MWH and foam demonstrated the most favorable impact on QoL, while NPWT showed more modest improvements, possibly due to patient complexity. Notably, the variable “sexuality” remained unchanged (mean = 0.00), possibly due to underreporting or communication barriers. <i>Conclusions</i>: Chronic wound treatments significantly improve patients’ quality of life, particularly in terms of pain and social functioning. The use of combined tools (DLQI and EQ-5D) allows for a more comprehensive understanding of these outcomes. These findings highlight the importance of tailoring wound care to individual needs and addressing psychosocial domains, including sexuality. Community nursing, nutritional support, and long-term follow-up should be incorporated into care plans to optimize results, especially in older adults. |
| format | Article |
| id | doaj-art-282f55673af84e8dab7c0da223938589 |
| institution | OA Journals |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj-art-282f55673af84e8dab7c0da2239385892025-08-20T02:33:57ZengMDPI AGMedicina1010-660X1648-91442025-05-0161590710.3390/medicina61050907Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5DDavid Palomar-Albert0Jorge Zamora-Ortiz1Federico Palomar-Llatas2Marta Escudero-Martínez3Alba Naranjo-Cuellar4Maria Isabel Pastor-Orduña5Integrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente Mártir, 46001 Valencia, SpainUlcers Unit, Valencia General Hospital Department, 46014 Valencia, SpainIntegrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente Mártir, 46001 Valencia, SpainIntegrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente Mártir, 46001 Valencia, SpainIntegrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente Mártir, 46001 Valencia, SpainIntegrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente Mártir, 46001 Valencia, Spain<i>Background and Objectives</i>: Chronic wounds severely impair patients’ quality of life (QoL), impacting physical, emotional, and functional well-being. Understanding the multidimensional effects of treatment is key to implementing effective, patient-centered care strategies. This study aimed to assess changes in QoL among patients with chronic wounds using the Dermatology Life Quality Index (DLQI) and EuroQol-5D (EQ-5D), comparing outcomes across treatment modalities. <i>Materials and Methods</i>: A longitudinal observational study was conducted between 2019 and 2024 across three hospitals in the Valencian Community. A total of 278 patients with venous lower-limb ulcers of more than six weeks’ duration were included. Quality-of-life assessments were performed at baseline, one-month follow-up, and discharge. Treatments included alginate, foam, moist wound healing (MWH), compression therapy, and negative-pressure wound therapy (NPWT). Statistical analysis involved Friedman’s test and repeated-measures ANOVA. <i>Results</i>: Significant improvements were observed in overall QoL across most treatment modalities. EQ-5D scores progressively increased, while DLQI scores decreased. Pain, embarrassment, and limitations in daily life (e.g., shopping and social activities) showed marked reductions. MWH and foam demonstrated the most favorable impact on QoL, while NPWT showed more modest improvements, possibly due to patient complexity. Notably, the variable “sexuality” remained unchanged (mean = 0.00), possibly due to underreporting or communication barriers. <i>Conclusions</i>: Chronic wound treatments significantly improve patients’ quality of life, particularly in terms of pain and social functioning. The use of combined tools (DLQI and EQ-5D) allows for a more comprehensive understanding of these outcomes. These findings highlight the importance of tailoring wound care to individual needs and addressing psychosocial domains, including sexuality. Community nursing, nutritional support, and long-term follow-up should be incorporated into care plans to optimize results, especially in older adults.https://www.mdpi.com/1648-9144/61/5/907chronic woundsquality of lifeDLQIEQ-5Dlongitudinal studywound treatment |
| spellingShingle | David Palomar-Albert Jorge Zamora-Ortiz Federico Palomar-Llatas Marta Escudero-Martínez Alba Naranjo-Cuellar Maria Isabel Pastor-Orduña Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D Medicina chronic wounds quality of life DLQI EQ-5D longitudinal study wound treatment |
| title | Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D |
| title_full | Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D |
| title_fullStr | Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D |
| title_full_unstemmed | Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D |
| title_short | Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D |
| title_sort | longitudinal observational study on quality of life in patients with chronic wounds using dlqi and eq 5d |
| topic | chronic wounds quality of life DLQI EQ-5D longitudinal study wound treatment |
| url | https://www.mdpi.com/1648-9144/61/5/907 |
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