Serum lipids at various stages and morpho-functional types of heart failure in patients with myocardial infarction
Venous blood levels of fatty acids (FA), ATP, and lipid peroxidation products, were examined in heart failure (HF) patients after myocardial infarction. These levels were measured at various stages and in various morpho-functional types ofHF. In more severe HF, FA metabolism was more disturbed, that...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2005-04-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2447 |
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| Summary: | Venous blood levels of fatty acids (FA), ATP, and lipid peroxidation products, were examined in heart failure (HF) patients after myocardial infarction. These levels were measured at various stages and in various morpho-functional types ofHF. In more severe HF, FA metabolism was more disturbed, that could be assessed by FA/glycerin coefficient, marker of myocardial insufficiency. In severe HF, ATP synthesis declined, and its level in peripheral blood reduced. By FA/ATP ratio, severity of myocardial insufficiency could be assessed; its greater figures were observed in dilated cardiomyopathy. Hypertrophic morpho-functional HFtype was characterized by less disturbed FA utilization and more pronounced activation of lipid peroxidation. Concentrations of blood biochemical markers, reflecting energy metabolism, correlated with cardiac hemodynamics parameters. |
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| ISSN: | 1560-4071 2618-7620 |