Effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake for adults with dysphagia: a meta-analysis of randomized controlled trials
Objectives: To determine and explore the effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake in adults with dysphagia. Participants: Adults with dysphagia. Design: A meta-analysis of randomized controlled trials (RCTs). Methods: We conducted a comprehensive li...
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Elsevier
2025-04-01
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| Series: | The Journal of Nutrition, Health and Aging |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1279770725000090 |
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| author | Yu-Hao Chu Jane C-J Chao |
| author_facet | Yu-Hao Chu Jane C-J Chao |
| author_sort | Yu-Hao Chu |
| collection | DOAJ |
| description | Objectives: To determine and explore the effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake in adults with dysphagia. Participants: Adults with dysphagia. Design: A meta-analysis of randomized controlled trials (RCTs). Methods: We conducted a comprehensive literature search in EMBASE, Cochrane Library, Ovid-Medline, CINAHL, Web of Science, PubMed, and reference lists until November 2023. Quality of the included studies was assessed by the Cochrane Risk of Bias Assessment tool 2.0. Data analysis was performed using Comprehensive Meta-analysis 3.0 for pooled Hedges’ g and odds ratios (ORs) with corresponding confidence interval (CI) adopting a random-effects model. A X2- based test using Cochran’s Q (P < 0.10) and I2 statistics evaluated heterogeneity. Results: In total, 16 RCTs from among 3,854 studies retrieved from the literature search with 1812 adults with dysphagia were included in this meta-analysis. Texture-modified diets revealed a significant small effect on increasing energy intake (g: 0.37, 95% CI = 0.05–0.68) and a medium effect on increasing protein intake (g: 0.56, 95% CI = 0.13–0.99). Thickened fluids revealed a significantly reduced risk of aspiration (OR: 0.59, 95% CI = 0.44–0.79), and thickened fluids combined with water protocol revealed a significant large effect on increasing fluid intake (g: 3.96, 95% C = 0.75–7.16). Conclusions: The findings of this meta-analysis demonstrated that texture-modified diets increase dietary intake of energy and protein for adults with dysphagia. In addition, thickened fluids reduced the risk of aspiration while thickened fluids combined with water protocol increased fluid intake in adults with dysphagia. |
| format | Article |
| id | doaj-art-2817c9b6439441caae85b0e4555b3f4f |
| institution | OA Journals |
| issn | 1760-4788 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | The Journal of Nutrition, Health and Aging |
| spelling | doaj-art-2817c9b6439441caae85b0e4555b3f4f2025-08-20T02:10:13ZengElsevierThe Journal of Nutrition, Health and Aging1760-47882025-04-0129410048610.1016/j.jnha.2025.100486Effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake for adults with dysphagia: a meta-analysis of randomized controlled trialsYu-Hao Chu0Jane C-J Chao1School of Nutrition and Health Sciences, Taipei Medical University, Taipei, TaiwanSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan; TMU Research Center for Digestive Medicine, Taipei Medical University, Taipei, Taiwan; Nutrition Research Center, Taipei Medical University Hospital, Taipei, Taiwan; Corresponding author.Objectives: To determine and explore the effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake in adults with dysphagia. Participants: Adults with dysphagia. Design: A meta-analysis of randomized controlled trials (RCTs). Methods: We conducted a comprehensive literature search in EMBASE, Cochrane Library, Ovid-Medline, CINAHL, Web of Science, PubMed, and reference lists until November 2023. Quality of the included studies was assessed by the Cochrane Risk of Bias Assessment tool 2.0. Data analysis was performed using Comprehensive Meta-analysis 3.0 for pooled Hedges’ g and odds ratios (ORs) with corresponding confidence interval (CI) adopting a random-effects model. A X2- based test using Cochran’s Q (P < 0.10) and I2 statistics evaluated heterogeneity. Results: In total, 16 RCTs from among 3,854 studies retrieved from the literature search with 1812 adults with dysphagia were included in this meta-analysis. Texture-modified diets revealed a significant small effect on increasing energy intake (g: 0.37, 95% CI = 0.05–0.68) and a medium effect on increasing protein intake (g: 0.56, 95% CI = 0.13–0.99). Thickened fluids revealed a significantly reduced risk of aspiration (OR: 0.59, 95% CI = 0.44–0.79), and thickened fluids combined with water protocol revealed a significant large effect on increasing fluid intake (g: 3.96, 95% C = 0.75–7.16). Conclusions: The findings of this meta-analysis demonstrated that texture-modified diets increase dietary intake of energy and protein for adults with dysphagia. In addition, thickened fluids reduced the risk of aspiration while thickened fluids combined with water protocol increased fluid intake in adults with dysphagia.http://www.sciencedirect.com/science/article/pii/S1279770725000090DysphagiaThickened fluidTexture-modified dietDietary nutrient intakeFluid intakeAspiration |
| spellingShingle | Yu-Hao Chu Jane C-J Chao Effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake for adults with dysphagia: a meta-analysis of randomized controlled trials The Journal of Nutrition, Health and Aging Dysphagia Thickened fluid Texture-modified diet Dietary nutrient intake Fluid intake Aspiration |
| title | Effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake for adults with dysphagia: a meta-analysis of randomized controlled trials |
| title_full | Effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake for adults with dysphagia: a meta-analysis of randomized controlled trials |
| title_fullStr | Effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake for adults with dysphagia: a meta-analysis of randomized controlled trials |
| title_full_unstemmed | Effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake for adults with dysphagia: a meta-analysis of randomized controlled trials |
| title_short | Effectiveness of diet modification on dietary nutrient intake, aspiration, and fluid intake for adults with dysphagia: a meta-analysis of randomized controlled trials |
| title_sort | effectiveness of diet modification on dietary nutrient intake aspiration and fluid intake for adults with dysphagia a meta analysis of randomized controlled trials |
| topic | Dysphagia Thickened fluid Texture-modified diet Dietary nutrient intake Fluid intake Aspiration |
| url | http://www.sciencedirect.com/science/article/pii/S1279770725000090 |
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