Determination of 5-fluorouracil anticancer drug solubility in supercritical CO 2 using semi-empirical and machine learning models
Abstract In order to provide the facilities to design the supercritical fluid (SCF) processes for micro or nanosizing of solid solute compounds such as drugs, it is essential to obtain their solubility in green solvents like pressurized CO2. This important role is the first stage for assessing each...
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Main Authors: | Gholamhossein Sodeifian, Ratna Surya Alwi, Reza Derakhsheshpour, Nedasadat Saadati Ardestani |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-02-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-87383-z |
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