Contrast-induced nephropathy in patients with acute coronary syndrome: clinical significance, diagnosis, prophylaxis

In modern medical practice, contrast-induced nephropathy (CIN) is an urgent problem in patients with acute coronary syndrome that underwent percutaneous interventions. It worsens prognosis, increases the number of cardiovascular complications and the length of hospital stay. Despite the use of moder...

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Main Authors: O. V. Demchuk, I. A. Sukmanova, I. V. Ponomarenko, V. A. Elykomov
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2020-04-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/2367
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author O. V. Demchuk
I. A. Sukmanova
I. V. Ponomarenko
V. A. Elykomov
author_facet O. V. Demchuk
I. A. Sukmanova
I. V. Ponomarenko
V. A. Elykomov
author_sort O. V. Demchuk
collection DOAJ
description In modern medical practice, contrast-induced nephropathy (CIN) is an urgent problem in patients with acute coronary syndrome that underwent percutaneous interventions. It worsens prognosis, increases the number of cardiovascular complications and the length of hospital stay. Despite the use of modern radiocontrast agents, the incidence of CIN can increase in a certain patients up to 50%. Risk factors for CIN can be associated both with the patient and directly with the x-ray procedures. The diagnosis is mainly based on the pre- and postprocedural determination of creatinine. However, more modern biomarkers of kidney injury can be used at present, which allow diagnosing the acute kidney injury as soon as possible. A huge role is played not only by treatment, but also by the prevention of CIN, which consists in the timely identification of high-risk patients. The current study presents the main points of pathogenesis, methods for diagnosing CIN, as well as methods for its prevention and treatment in patients with acute coronary syndrome.
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institution DOAJ
issn 1728-8800
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language Russian
publishDate 2020-04-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-27fb566450dd4fbc853db437e7ef2fd02025-08-20T02:59:15Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252020-04-0119210.15829/1728-8800-2019-22551995Contrast-induced nephropathy in patients with acute coronary syndrome: clinical significance, diagnosis, prophylaxisO. V. Demchuk0I. A. Sukmanova1I. V. Ponomarenko2V. A. Elykomov3Altai Regional Cardiology DispensaryAltai Regional Cardiology Dispensary; Altai State Medical UniversityAltai Regional Cardiology DispensaryAltai State Medical UniversityIn modern medical practice, contrast-induced nephropathy (CIN) is an urgent problem in patients with acute coronary syndrome that underwent percutaneous interventions. It worsens prognosis, increases the number of cardiovascular complications and the length of hospital stay. Despite the use of modern radiocontrast agents, the incidence of CIN can increase in a certain patients up to 50%. Risk factors for CIN can be associated both with the patient and directly with the x-ray procedures. The diagnosis is mainly based on the pre- and postprocedural determination of creatinine. However, more modern biomarkers of kidney injury can be used at present, which allow diagnosing the acute kidney injury as soon as possible. A huge role is played not only by treatment, but also by the prevention of CIN, which consists in the timely identification of high-risk patients. The current study presents the main points of pathogenesis, methods for diagnosing CIN, as well as methods for its prevention and treatment in patients with acute coronary syndrome.https://cardiovascular.elpub.ru/jour/article/view/2367contrast-induced nephropathyacute coronary syndromeradiocontrast agentsbiomarkersacute kidney injury
spellingShingle O. V. Demchuk
I. A. Sukmanova
I. V. Ponomarenko
V. A. Elykomov
Contrast-induced nephropathy in patients with acute coronary syndrome: clinical significance, diagnosis, prophylaxis
Кардиоваскулярная терапия и профилактика
contrast-induced nephropathy
acute coronary syndrome
radiocontrast agents
biomarkers
acute kidney injury
title Contrast-induced nephropathy in patients with acute coronary syndrome: clinical significance, diagnosis, prophylaxis
title_full Contrast-induced nephropathy in patients with acute coronary syndrome: clinical significance, diagnosis, prophylaxis
title_fullStr Contrast-induced nephropathy in patients with acute coronary syndrome: clinical significance, diagnosis, prophylaxis
title_full_unstemmed Contrast-induced nephropathy in patients with acute coronary syndrome: clinical significance, diagnosis, prophylaxis
title_short Contrast-induced nephropathy in patients with acute coronary syndrome: clinical significance, diagnosis, prophylaxis
title_sort contrast induced nephropathy in patients with acute coronary syndrome clinical significance diagnosis prophylaxis
topic contrast-induced nephropathy
acute coronary syndrome
radiocontrast agents
biomarkers
acute kidney injury
url https://cardiovascular.elpub.ru/jour/article/view/2367
work_keys_str_mv AT ovdemchuk contrastinducednephropathyinpatientswithacutecoronarysyndromeclinicalsignificancediagnosisprophylaxis
AT iasukmanova contrastinducednephropathyinpatientswithacutecoronarysyndromeclinicalsignificancediagnosisprophylaxis
AT ivponomarenko contrastinducednephropathyinpatientswithacutecoronarysyndromeclinicalsignificancediagnosisprophylaxis
AT vaelykomov contrastinducednephropathyinpatientswithacutecoronarysyndromeclinicalsignificancediagnosisprophylaxis