Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in Minipigs

Despite being considered noncritical size defects, extraction sockets often require the use of bone grafts or bone graft substitutes in order to facilitate a stable implant site with an aesthetically pleasing mucosal architecture and prosthetic reconstruction. In the present study, the effect of nov...

Full description

Saved in:
Bibliographic Details
Main Authors: Hanna Tiainen, Anders Verket, Håvard J. Haugen, S. Petter Lyngstadaas, Johan Caspar Wohlfahrt
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2012/851264
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850229144524161024
author Hanna Tiainen
Anders Verket
Håvard J. Haugen
S. Petter Lyngstadaas
Johan Caspar Wohlfahrt
author_facet Hanna Tiainen
Anders Verket
Håvard J. Haugen
S. Petter Lyngstadaas
Johan Caspar Wohlfahrt
author_sort Hanna Tiainen
collection DOAJ
description Despite being considered noncritical size defects, extraction sockets often require the use of bone grafts or bone graft substitutes in order to facilitate a stable implant site with an aesthetically pleasing mucosal architecture and prosthetic reconstruction. In the present study, the effect of novel TiO2 scaffolds on dimensional ridge preservation was evaluated following their placement into surgically modified extraction sockets in the premolar region of minipig mandibles. After six weeks of healing, the scaffolds were wellintegrated in the alveolar bone, and the convex shape of the alveolar crest was preserved. The scaffolds were found to partially preserve the dimensions of the native buccal and lingual bone walls adjacent to the defect site. A tendency towards more pronounced vertical ridge resorption, particularly in the buccal bone wall of the nongrafted alveoli, indicates that the TiO2 scaffold may be used for suppressing the loss of bone that normally follows tooth extraction.
format Article
id doaj-art-27f9fbefedfc4cb8876af967f5ac5c85
institution OA Journals
issn 1687-8787
1687-8795
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series International Journal of Biomaterials
spelling doaj-art-27f9fbefedfc4cb8876af967f5ac5c852025-08-20T02:04:19ZengWileyInternational Journal of Biomaterials1687-87871687-87952012-01-01201210.1155/2012/851264851264Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in MinipigsHanna Tiainen0Anders Verket1Håvard J. Haugen2S. Petter Lyngstadaas3Johan Caspar Wohlfahrt4Department of Biomaterials, Institute for Clinical Dentistry, University of Oslo, PO Box 1109, Blindern, 0317 Oslo, NorwayDepartment of Biomaterials, Institute for Clinical Dentistry, University of Oslo, PO Box 1109, Blindern, 0317 Oslo, NorwayDepartment of Biomaterials, Institute for Clinical Dentistry, University of Oslo, PO Box 1109, Blindern, 0317 Oslo, NorwayDepartment of Biomaterials, Institute for Clinical Dentistry, University of Oslo, PO Box 1109, Blindern, 0317 Oslo, NorwayDepartment of Biomaterials, Institute for Clinical Dentistry, University of Oslo, PO Box 1109, Blindern, 0317 Oslo, NorwayDespite being considered noncritical size defects, extraction sockets often require the use of bone grafts or bone graft substitutes in order to facilitate a stable implant site with an aesthetically pleasing mucosal architecture and prosthetic reconstruction. In the present study, the effect of novel TiO2 scaffolds on dimensional ridge preservation was evaluated following their placement into surgically modified extraction sockets in the premolar region of minipig mandibles. After six weeks of healing, the scaffolds were wellintegrated in the alveolar bone, and the convex shape of the alveolar crest was preserved. The scaffolds were found to partially preserve the dimensions of the native buccal and lingual bone walls adjacent to the defect site. A tendency towards more pronounced vertical ridge resorption, particularly in the buccal bone wall of the nongrafted alveoli, indicates that the TiO2 scaffold may be used for suppressing the loss of bone that normally follows tooth extraction.http://dx.doi.org/10.1155/2012/851264
spellingShingle Hanna Tiainen
Anders Verket
Håvard J. Haugen
S. Petter Lyngstadaas
Johan Caspar Wohlfahrt
Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in Minipigs
International Journal of Biomaterials
title Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in Minipigs
title_full Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in Minipigs
title_fullStr Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in Minipigs
title_full_unstemmed Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in Minipigs
title_short Dimensional Ridge Preservation with a Novel Highly Porous TiO 2 Scaffold: An Experimental Study in Minipigs
title_sort dimensional ridge preservation with a novel highly porous tio 2 scaffold an experimental study in minipigs
url http://dx.doi.org/10.1155/2012/851264
work_keys_str_mv AT hannatiainen dimensionalridgepreservationwithanovelhighlyporoustio2scaffoldanexperimentalstudyinminipigs
AT andersverket dimensionalridgepreservationwithanovelhighlyporoustio2scaffoldanexperimentalstudyinminipigs
AT havardjhaugen dimensionalridgepreservationwithanovelhighlyporoustio2scaffoldanexperimentalstudyinminipigs
AT spetterlyngstadaas dimensionalridgepreservationwithanovelhighlyporoustio2scaffoldanexperimentalstudyinminipigs
AT johancasparwohlfahrt dimensionalridgepreservationwithanovelhighlyporoustio2scaffoldanexperimentalstudyinminipigs