Nitrous Oxide Persistently Alleviates Pain Hypersensitivity in Neuropathic Rats: A Dose-Dependent Effect

BACKGROUND: Despite numerous pharmacological approaches, there are no common analgesic drugs that produce meaningful relief for the majority of patients with neuropathic pain. Although nitrous oxide (N2O) is a weak analgesic that acts via opioid-dependent mechanisms, it is also an antagonist of the...

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Bibliographic Details
Main Authors: Meric Ben Boujema, Emilie Laboureyras, Jan Pype, Baptiste Bessière, Guy Simonnet
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2015/809059
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