Potential protective regulatory effects on radiation−induced esophageal injury in TUT4−/− mice

Potential protective regulatory effects on radiation−induced esophageal injury in TUT4−/− mice

IntroductionTerminal uridyl transferase 4 (TUT4), a nucleotide transferase that modifies miRNA sequences, plays a critical role in regulating miRNA target interactions and function. However, its involvement in radiation-induced esophageal injury remains poorly understood.MethodsTo investigate this,...

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Bibliographic Details
Main Authors: Huiwen Ren, Wei Li, Zhigang Fan, Jianlin Wang, Zhiqiang Sun, Renhua Huang, Judong Luo, Bo Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
esophageal tissue
radioprotection
TUT4
radiation-induced esophageal injury
radioactivity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1600597/full
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