Guillain–Barre Syndrome following SARS-COVID-19 Infection: A Case Report from India

Severe acute respiratory syndrome coronavirus 2 (SARS-COVID-19) is a novel coronavirus that started in Wuhan City in China in December 2019. It can cause acute respiratory infection. Guillain–Barre syndrome (GBS) is an autoimmune disease characterized by rapidly progressing ascending paralysis that...

Full description

Saved in:
Bibliographic Details
Main Authors: Abhishek Singhai, Akshit Budhiraja
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2021/4676659
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849307753407840256
author Abhishek Singhai
Akshit Budhiraja
author_facet Abhishek Singhai
Akshit Budhiraja
author_sort Abhishek Singhai
collection DOAJ
description Severe acute respiratory syndrome coronavirus 2 (SARS-COVID-19) is a novel coronavirus that started in Wuhan City in China in December 2019. It can cause acute respiratory infection. Guillain–Barre syndrome (GBS) is an autoimmune disease characterized by rapidly progressing ascending paralysis that is triggered by an infection or immune stimulation which produces an abnormal immune response that targets peripheral nerves. In most cases, it is preceded by a bacterial or viral infection. This is a case of a 36-year-old male patient from India who developed progressive acute flaccid paralysis after SARS-COVID-19 infection. Clinical examination and lab studies lead to the diagnosis of GBS. The patient was treated with intravenous immunoglobulins and supportive treatment. Following treatment, there was a substantial improvement in weakness as reported by the patient and was confirmed by clinical evaluation. This is an uncommon manifestation of SARS-COVID-19 infection and suggests the presence of an immune-mediated process leading to damage of the nervous system.
format Article
id doaj-art-27eeea18785147009dbbadcdd5f25a8e
institution Kabale University
issn 2090-6625
2090-6633
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Infectious Diseases
spelling doaj-art-27eeea18785147009dbbadcdd5f25a8e2025-08-20T03:54:38ZengWileyCase Reports in Infectious Diseases2090-66252090-66332021-01-01202110.1155/2021/46766594676659Guillain–Barre Syndrome following SARS-COVID-19 Infection: A Case Report from IndiaAbhishek Singhai0Akshit Budhiraja1Department of Medicine, All India Institute of Medical Sciences, Bhopal, IndiaDepartment of Medicine, All India Institute of Medical Sciences, Bhopal, IndiaSevere acute respiratory syndrome coronavirus 2 (SARS-COVID-19) is a novel coronavirus that started in Wuhan City in China in December 2019. It can cause acute respiratory infection. Guillain–Barre syndrome (GBS) is an autoimmune disease characterized by rapidly progressing ascending paralysis that is triggered by an infection or immune stimulation which produces an abnormal immune response that targets peripheral nerves. In most cases, it is preceded by a bacterial or viral infection. This is a case of a 36-year-old male patient from India who developed progressive acute flaccid paralysis after SARS-COVID-19 infection. Clinical examination and lab studies lead to the diagnosis of GBS. The patient was treated with intravenous immunoglobulins and supportive treatment. Following treatment, there was a substantial improvement in weakness as reported by the patient and was confirmed by clinical evaluation. This is an uncommon manifestation of SARS-COVID-19 infection and suggests the presence of an immune-mediated process leading to damage of the nervous system.http://dx.doi.org/10.1155/2021/4676659
spellingShingle Abhishek Singhai
Akshit Budhiraja
Guillain–Barre Syndrome following SARS-COVID-19 Infection: A Case Report from India
Case Reports in Infectious Diseases
title Guillain–Barre Syndrome following SARS-COVID-19 Infection: A Case Report from India
title_full Guillain–Barre Syndrome following SARS-COVID-19 Infection: A Case Report from India
title_fullStr Guillain–Barre Syndrome following SARS-COVID-19 Infection: A Case Report from India
title_full_unstemmed Guillain–Barre Syndrome following SARS-COVID-19 Infection: A Case Report from India
title_short Guillain–Barre Syndrome following SARS-COVID-19 Infection: A Case Report from India
title_sort guillain barre syndrome following sars covid 19 infection a case report from india
url http://dx.doi.org/10.1155/2021/4676659
work_keys_str_mv AT abhisheksinghai guillainbarresyndromefollowingsarscovid19infectionacasereportfromindia
AT akshitbudhiraja guillainbarresyndromefollowingsarscovid19infectionacasereportfromindia