Acute effects of oral mesna administration on the full amino acid profile and 3-methylhistidine: secondary results from the CYLOB dose-finding study
Abstract Plasma total cysteine (tCys) is strongly associated with fat mass in humans. Mesna lowers plasma tCys in a dose-dependent manner, but it is not known whether it interferes with metabolism of other amino acids or protein. In this Phase-1 study, we show that a single dose of mesna administere...
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| Main Authors: | Thomas Olsen, Amany Elshorbagy, Emma Stolt, Anders Åsberg, Hasse K. Zaré, Nasser E. Bastani, Helga Refsum, Kjetil Retterstøl, Kathrine J. Vinknes |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2024-06-01
|
| Series: | Amino Acids |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00726-024-03398-2 |
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