RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish

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Main Authors: Ke Zhang, Botong Li, Zhiling Deng, Yong Dong, Yuanyuan Li, Bingyu Chen, Mao Lu, Liyan Wang, Xingdong Liu, Zhenhua Guo, Sizhou Huang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224002836
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author Ke Zhang
Botong Li
Zhiling Deng
Yong Dong
Yuanyuan Li
Bingyu Chen
Mao Lu
Liyan Wang
Xingdong Liu
Zhenhua Guo
Sizhou Huang
author_facet Ke Zhang
Botong Li
Zhiling Deng
Yong Dong
Yuanyuan Li
Bingyu Chen
Mao Lu
Liyan Wang
Xingdong Liu
Zhenhua Guo
Sizhou Huang
author_sort Ke Zhang
collection DOAJ
format Article
id doaj-art-27e2ab54a5604afe8c37fc83c94445de
institution DOAJ
issn 2352-3042
language English
publishDate 2025-09-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Genes and Diseases
spelling doaj-art-27e2ab54a5604afe8c37fc83c94445de2025-08-20T03:15:02ZengKeAi Communications Co., Ltd.Genes and Diseases2352-30422025-09-0112510148610.1016/j.gendis.2024.101486RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafishKe Zhang0Botong Li1Zhiling Deng2Yong Dong3Yuanyuan Li4Bingyu Chen5Mao Lu6Liyan Wang7Xingdong Liu8Zhenhua Guo9Sizhou Huang10Development and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, China; Central Hospital of Suining, Suining, Sichuan 629000, ChinaDevelopment and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, ChinaDevelopment and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, ChinaDevelopment and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, ChinaDepartment of Neurology, The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, Sichuan 610000, ChinaDevelopment and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, ChinaDepartment of Dermatovenereology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan 610500, ChinaDevelopment and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, ChinaDepartment of Neurology, The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, Sichuan 610000, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, CSTC2009CA5002, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, China; Corresponding author.Development and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histology and Embryology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, China; Department of Neurology, The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, Sichuan 610000, China; Corresponding author. Development and Regeneration Key Laboratory of Sichuan Province, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, Sichuan 610500, China.http://www.sciencedirect.com/science/article/pii/S2352304224002836
spellingShingle Ke Zhang
Botong Li
Zhiling Deng
Yong Dong
Yuanyuan Li
Bingyu Chen
Mao Lu
Liyan Wang
Xingdong Liu
Zhenhua Guo
Sizhou Huang
RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish
Genes and Diseases
title RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish
title_full RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish
title_fullStr RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish
title_full_unstemmed RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish
title_short RNA-seq identifies Amd1 as a regulator of hepatocyte proliferation via Skp2 during liver development and hepatocellular carcinoma progression in zebrafish
title_sort rna seq identifies amd1 as a regulator of hepatocyte proliferation via skp2 during liver development and hepatocellular carcinoma progression in zebrafish
url http://www.sciencedirect.com/science/article/pii/S2352304224002836
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