ESTIMATION OF HEALTHY AND LIVER DISEASED INDIVIDUALS BY A LINEAR REGRESSION CLASSIFICATION ALGORITHM

Objective: In this study, the aim was to make a categorical estimation of the absent/presence of liver disease by using some blood biochemistry parameters (ALB, ALP, ALT, AST, BIL, CHE, CHOL, CREA, GGT, and PROT), gender and the age of healthy individuals, and those with liver disease.Material and m...

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Main Author: Handan Tanyıldızı Kökkülünk
Format: Article
Language:English
Published: Istanbul University Press 2023-10-01
Series:Sabiad
Subjects:
Online Access:https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/162A430DAC294FD89644F67D130ACF55
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author Handan Tanyıldızı Kökkülünk
author_facet Handan Tanyıldızı Kökkülünk
author_sort Handan Tanyıldızı Kökkülünk
collection DOAJ
description Objective: In this study, the aim was to make a categorical estimation of the absent/presence of liver disease by using some blood biochemistry parameters (ALB, ALP, ALT, AST, BIL, CHE, CHOL, CREA, GGT, and PROT), gender and the age of healthy individuals, and those with liver disease.Material and methods: The prediction was obtained with multiple linear regression of machine learning in the R Studio program. Machine learning was improved by selecting parameters that have a high contribution to the prediction by using the Akaike information criterion.Results: The three strongest parameters with a positive effect on the estimation were AST, BIL, and GGT, respectively; The three strongest parameters with negative effects were CHOL, CHE, and ALB, respectively. The accuracy of the model used was 91%, the precision was 99%, the recall was 0.91, and the F score was 94%. When the correlation relationship graph was examined, it was determined that AST was a strong differential parameter in healthy/liver diseased individuals.Conclusion: Multiple linear regression is a preferable method for categorical disease classification.
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institution Kabale University
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publishDate 2023-10-01
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spelling doaj-art-27e1b399be904f9cb6d6423b30bdd9362025-08-20T03:53:07ZengIstanbul University PressSabiad2651-40602023-10-016322923310.26650/JARHS2023-1231512123456ESTIMATION OF HEALTHY AND LIVER DISEASED INDIVIDUALS BY A LINEAR REGRESSION CLASSIFICATION ALGORITHMHandan Tanyıldızı Kökkülünk0https://orcid.org/0000-0001-5231-2768Altınbaş Üniversitesi, Istanbul, TurkiyeObjective: In this study, the aim was to make a categorical estimation of the absent/presence of liver disease by using some blood biochemistry parameters (ALB, ALP, ALT, AST, BIL, CHE, CHOL, CREA, GGT, and PROT), gender and the age of healthy individuals, and those with liver disease.Material and methods: The prediction was obtained with multiple linear regression of machine learning in the R Studio program. Machine learning was improved by selecting parameters that have a high contribution to the prediction by using the Akaike information criterion.Results: The three strongest parameters with a positive effect on the estimation were AST, BIL, and GGT, respectively; The three strongest parameters with negative effects were CHOL, CHE, and ALB, respectively. The accuracy of the model used was 91%, the precision was 99%, the recall was 0.91, and the F score was 94%. When the correlation relationship graph was examined, it was determined that AST was a strong differential parameter in healthy/liver diseased individuals.Conclusion: Multiple linear regression is a preferable method for categorical disease classification.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/162A430DAC294FD89644F67D130ACF55machine learningliverclassification
spellingShingle Handan Tanyıldızı Kökkülünk
ESTIMATION OF HEALTHY AND LIVER DISEASED INDIVIDUALS BY A LINEAR REGRESSION CLASSIFICATION ALGORITHM
Sabiad
machine learning
liver
classification
title ESTIMATION OF HEALTHY AND LIVER DISEASED INDIVIDUALS BY A LINEAR REGRESSION CLASSIFICATION ALGORITHM
title_full ESTIMATION OF HEALTHY AND LIVER DISEASED INDIVIDUALS BY A LINEAR REGRESSION CLASSIFICATION ALGORITHM
title_fullStr ESTIMATION OF HEALTHY AND LIVER DISEASED INDIVIDUALS BY A LINEAR REGRESSION CLASSIFICATION ALGORITHM
title_full_unstemmed ESTIMATION OF HEALTHY AND LIVER DISEASED INDIVIDUALS BY A LINEAR REGRESSION CLASSIFICATION ALGORITHM
title_short ESTIMATION OF HEALTHY AND LIVER DISEASED INDIVIDUALS BY A LINEAR REGRESSION CLASSIFICATION ALGORITHM
title_sort estimation of healthy and liver diseased individuals by a linear regression classification algorithm
topic machine learning
liver
classification
url https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/162A430DAC294FD89644F67D130ACF55
work_keys_str_mv AT handantanyıldızıkokkulunk estimationofhealthyandliverdiseasedindividualsbyalinearregressionclassificationalgorithm