Trueperella pyogenes promotes the synthesis and maturation of IL-1β in murine macrophages

Trueperella pyogenes promotes the synthesis and maturation of IL-1β in murine macrophages

Trueperella pyogenes (T. pyogenes) is an important opportunistic pathogen in animals and can also cause diseases in humans. Previous studies have shown that T. pyogenes infection can upregulate the levels of pro-inflammatory cytokines, such as interleukin-1 beta (IL-1β), in host tissues. However, th...

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Bibliographic Details
Main Authors: Meimei Yang, Yunhao Hu, Junwei Wang, Wenlong Zhang, Bin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
T. pyogenes
PLO
NF-κB
NLRP3
caspase-1
IL-1β
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1614952/full
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