Effectiveness of Nursing Interventions on Preventing the Risk of Infection in Adult Inpatients: Protocol for a Systematic Review
<b>Background/Objectives:</b> Healthcare-associated infections (HAIs) are a major global public health concern, significantly impacting patient safety and healthcare quality. These infections are associated with high morbidity and mortality rates, prolonged hospital stays, and increased...
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MDPI AG
2025-06-01
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| Series: | Nursing Reports |
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| author | Luís Filipe Pereira Todo Bom Ema Soraia Fazenda Mata Helena Margarida Pereira Cunha Maria do Céu Mendes Pinto Marquês Maria dos Anjos Dixe |
| author_facet | Luís Filipe Pereira Todo Bom Ema Soraia Fazenda Mata Helena Margarida Pereira Cunha Maria do Céu Mendes Pinto Marquês Maria dos Anjos Dixe |
| author_sort | Luís Filipe Pereira Todo Bom |
| collection | DOAJ |
| description | <b>Background/Objectives:</b> Healthcare-associated infections (HAIs) are a major global public health concern, significantly impacting patient safety and healthcare quality. These infections are associated with high morbidity and mortality rates, prolonged hospital stays, and increased healthcare costs. Nurses play a critical role in infection prevention, implementing evidence-based interventions to reduce infection risks. This systematic review aims to identify and synthesize the most effective nursing interventions to prevent HAIs in hospitalized adults, analyzing their variability across different clinical settings and populations. <b>Methods:</b> This systematic review follows the Joanna Briggs Institute (JBI) methodology for systematic reviews of effectiveness and is reported according to PRISMA guidelines. The protocol is registered in the PROSPERO database (CRD42024582820). This review includes randomized controlled trials, quasi-experimental studies, and observational studies (cohort, case-control, and cross-sectional) assessing the effectiveness of nursing interventions in reducing HAIs. A comprehensive search is conducted in the PubMed, CINAHL, Scopus, Web of Science, and Cochrane databases. Study selection, data extraction, and quality assessment are performed by two independent reviewers, with disagreements resolved by a third reviewer. <b>Results:</b> The primary outcomes include reductions in HAI incidence rate, increased adherence to preventive interventions, decreased hospital length of stay, reduced readmission rates due to infections, and overall patient safety improvements. A meta-analysis is conducted when feasible; otherwise, results are synthesized narratively. <b>Conclusions:</b> The findings of this review contribute to the standardization of evidence-based nursing practices for HAI prevention, promoting safer healthcare environments. By identifying the most effective interventions, this study aims to support healthcare professionals and policymakers in implementing targeted infection control strategies. |
| format | Article |
| id | doaj-art-27db379296364e109f3f51d5bc521703 |
| institution | OA Journals |
| issn | 2039-439X 2039-4403 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nursing Reports |
| spelling | doaj-art-27db379296364e109f3f51d5bc5217032025-08-20T02:21:49ZengMDPI AGNursing Reports2039-439X2039-44032025-06-0115621010.3390/nursrep15060210Effectiveness of Nursing Interventions on Preventing the Risk of Infection in Adult Inpatients: Protocol for a Systematic ReviewLuís Filipe Pereira Todo Bom0Ema Soraia Fazenda Mata1Helena Margarida Pereira Cunha2Maria do Céu Mendes Pinto Marquês3Maria dos Anjos Dixe4Comprehensive Health Research Centre (CHRC), University of Évora, 7000-801 Évora, PortugalSchool of Health Sciences, Polytechnic University of Leiria, Campus 2, Morro do Lena, Alto do Vieiro, Apartado 4137, 2411-901 Leiria, PortugalSchool of Health Sciences, Polytechnic University of Leiria, Campus 2, Morro do Lena, Alto do Vieiro, Apartado 4137, 2411-901 Leiria, PortugalComprehensive Health Research Centre (CHRC), University of Évora, 7000-801 Évora, PortugalSchool of Health Sciences, Polytechnic University of Leiria, Campus 2, Morro do Lena, Alto do Vieiro, Apartado 4137, 2411-901 Leiria, Portugal<b>Background/Objectives:</b> Healthcare-associated infections (HAIs) are a major global public health concern, significantly impacting patient safety and healthcare quality. These infections are associated with high morbidity and mortality rates, prolonged hospital stays, and increased healthcare costs. Nurses play a critical role in infection prevention, implementing evidence-based interventions to reduce infection risks. This systematic review aims to identify and synthesize the most effective nursing interventions to prevent HAIs in hospitalized adults, analyzing their variability across different clinical settings and populations. <b>Methods:</b> This systematic review follows the Joanna Briggs Institute (JBI) methodology for systematic reviews of effectiveness and is reported according to PRISMA guidelines. The protocol is registered in the PROSPERO database (CRD42024582820). This review includes randomized controlled trials, quasi-experimental studies, and observational studies (cohort, case-control, and cross-sectional) assessing the effectiveness of nursing interventions in reducing HAIs. A comprehensive search is conducted in the PubMed, CINAHL, Scopus, Web of Science, and Cochrane databases. Study selection, data extraction, and quality assessment are performed by two independent reviewers, with disagreements resolved by a third reviewer. <b>Results:</b> The primary outcomes include reductions in HAI incidence rate, increased adherence to preventive interventions, decreased hospital length of stay, reduced readmission rates due to infections, and overall patient safety improvements. A meta-analysis is conducted when feasible; otherwise, results are synthesized narratively. <b>Conclusions:</b> The findings of this review contribute to the standardization of evidence-based nursing practices for HAI prevention, promoting safer healthcare environments. By identifying the most effective interventions, this study aims to support healthcare professionals and policymakers in implementing targeted infection control strategies.https://www.mdpi.com/2039-4403/15/6/210healthcare-associated infectionsnursing interventionsinfection preventionpatient safetysystematic review |
| spellingShingle | Luís Filipe Pereira Todo Bom Ema Soraia Fazenda Mata Helena Margarida Pereira Cunha Maria do Céu Mendes Pinto Marquês Maria dos Anjos Dixe Effectiveness of Nursing Interventions on Preventing the Risk of Infection in Adult Inpatients: Protocol for a Systematic Review Nursing Reports healthcare-associated infections nursing interventions infection prevention patient safety systematic review |
| title | Effectiveness of Nursing Interventions on Preventing the Risk of Infection in Adult Inpatients: Protocol for a Systematic Review |
| title_full | Effectiveness of Nursing Interventions on Preventing the Risk of Infection in Adult Inpatients: Protocol for a Systematic Review |
| title_fullStr | Effectiveness of Nursing Interventions on Preventing the Risk of Infection in Adult Inpatients: Protocol for a Systematic Review |
| title_full_unstemmed | Effectiveness of Nursing Interventions on Preventing the Risk of Infection in Adult Inpatients: Protocol for a Systematic Review |
| title_short | Effectiveness of Nursing Interventions on Preventing the Risk of Infection in Adult Inpatients: Protocol for a Systematic Review |
| title_sort | effectiveness of nursing interventions on preventing the risk of infection in adult inpatients protocol for a systematic review |
| topic | healthcare-associated infections nursing interventions infection prevention patient safety systematic review |
| url | https://www.mdpi.com/2039-4403/15/6/210 |
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