How influenza A virus NS1 impedes transcription of the host cell’s messenger RNAs

How influenza virus non-structural protein NS1 inhibits the activity of nuclear speckles, these liquid-liquid phase separation complexes that control the transcription and post-transcriptional regulation of cellular genes.

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Bibliographic Details
Main Author: Daniel Marc
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Viruses
Online Access:https://doi.org/10.1038/s44298-025-00137-6
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author Daniel Marc
author_facet Daniel Marc
author_sort Daniel Marc
collection DOAJ
description How influenza virus non-structural protein NS1 inhibits the activity of nuclear speckles, these liquid-liquid phase separation complexes that control the transcription and post-transcriptional regulation of cellular genes.
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institution Kabale University
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series npj Viruses
spelling doaj-art-27d22a3da8de4116869eedcd7c41f14c2025-08-20T04:01:52ZengNature Portfolionpj Viruses2948-17672025-07-01311210.1038/s44298-025-00137-6How influenza A virus NS1 impedes transcription of the host cell’s messenger RNAsDaniel Marc0Infectiologie et Santé Publique, INRAE, Université de ToursHow influenza virus non-structural protein NS1 inhibits the activity of nuclear speckles, these liquid-liquid phase separation complexes that control the transcription and post-transcriptional regulation of cellular genes.https://doi.org/10.1038/s44298-025-00137-6
spellingShingle Daniel Marc
How influenza A virus NS1 impedes transcription of the host cell’s messenger RNAs
npj Viruses
title How influenza A virus NS1 impedes transcription of the host cell’s messenger RNAs
title_full How influenza A virus NS1 impedes transcription of the host cell’s messenger RNAs
title_fullStr How influenza A virus NS1 impedes transcription of the host cell’s messenger RNAs
title_full_unstemmed How influenza A virus NS1 impedes transcription of the host cell’s messenger RNAs
title_short How influenza A virus NS1 impedes transcription of the host cell’s messenger RNAs
title_sort how influenza a virus ns1 impedes transcription of the host cell s messenger rnas
url https://doi.org/10.1038/s44298-025-00137-6
work_keys_str_mv AT danielmarc howinfluenzaavirusns1impedestranscriptionofthehostcellsmessengerrnas