POOLED PHENOTYPING OF MYH7 VARIANTS IN GENE-EDITED STEM CELL-DERIVED CARDIOMYOCYTES ENABLES RECLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCE
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | Journal of Molecular and Cellular Cardiology Plus |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772976125000959 |
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| _version_ | 1849424572858761216 |
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| author | Clayton Friedman Shawn Fayer Charles Murry Lea Starita Douglas Fowler Kai-Chun Yang |
| author_facet | Clayton Friedman Shawn Fayer Charles Murry Lea Starita Douglas Fowler Kai-Chun Yang |
| author_sort | Clayton Friedman |
| collection | DOAJ |
| format | Article |
| id | doaj-art-27c8caada0a64a949734de460c6b93cc |
| institution | Kabale University |
| issn | 2772-9761 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Molecular and Cellular Cardiology Plus |
| spelling | doaj-art-27c8caada0a64a949734de460c6b93cc2025-08-20T03:30:08ZengElsevierJournal of Molecular and Cellular Cardiology Plus2772-97612025-06-011210037610.1016/j.jmccpl.2025.100376POOLED PHENOTYPING OF MYH7 VARIANTS IN GENE-EDITED STEM CELL-DERIVED CARDIOMYOCYTES ENABLES RECLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCEClayton Friedman0Shawn Fayer1Charles Murry2Lea Starita3Douglas Fowler4Kai-Chun Yang5Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, USA; Center for Cardiovascular Biology, University of Washington, Seattle, USA; Department of Medicine/Cardiology, University of Washington, Seattle, USA; Corresponding author.Department of Genome Sciences, University of Washington, Seattle, USAInstitute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, USA; Center for Cardiovascular Biology, University of Washington, Seattle, USA; Department of Medicine/Cardiology, University of Washington, Seattle, USA; Department of Laboratory Medicine & Pathology, University of Washington, Seattle, USA; Department of Bioengineering, University of Washington, Seattle, USADepartment of Genome Sciences, University of Washington, Seattle, USA; Brotman Baty Institute for Precision Medicine, Seattle, USADepartment of Genome Sciences, University of Washington, Seattle, USA; Department of Bioengineering, University of Washington, Seattle, USA; Brotman Baty Institute for Precision Medicine, Seattle, USAInstitute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, USA; Center for Cardiovascular Biology, University of Washington, Seattle, USA; Department of Medicine/Cardiology, University of Washington, Seattle, USA; Cardiology/Hospital Specialty Medicine, VA Puget Sound HCS, Seattle, USAhttp://www.sciencedirect.com/science/article/pii/S2772976125000959 |
| spellingShingle | Clayton Friedman Shawn Fayer Charles Murry Lea Starita Douglas Fowler Kai-Chun Yang POOLED PHENOTYPING OF MYH7 VARIANTS IN GENE-EDITED STEM CELL-DERIVED CARDIOMYOCYTES ENABLES RECLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCE Journal of Molecular and Cellular Cardiology Plus |
| title | POOLED PHENOTYPING OF MYH7 VARIANTS IN GENE-EDITED STEM CELL-DERIVED CARDIOMYOCYTES ENABLES RECLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCE |
| title_full | POOLED PHENOTYPING OF MYH7 VARIANTS IN GENE-EDITED STEM CELL-DERIVED CARDIOMYOCYTES ENABLES RECLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCE |
| title_fullStr | POOLED PHENOTYPING OF MYH7 VARIANTS IN GENE-EDITED STEM CELL-DERIVED CARDIOMYOCYTES ENABLES RECLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCE |
| title_full_unstemmed | POOLED PHENOTYPING OF MYH7 VARIANTS IN GENE-EDITED STEM CELL-DERIVED CARDIOMYOCYTES ENABLES RECLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCE |
| title_short | POOLED PHENOTYPING OF MYH7 VARIANTS IN GENE-EDITED STEM CELL-DERIVED CARDIOMYOCYTES ENABLES RECLASSIFICATION OF VARIANTS OF UNKNOWN SIGNIFICANCE |
| title_sort | pooled phenotyping of myh7 variants in gene edited stem cell derived cardiomyocytes enables reclassification of variants of unknown significance |
| url | http://www.sciencedirect.com/science/article/pii/S2772976125000959 |
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