Mapping snoRNA-target RNA interactions in an RNA-binding protein-dependent manner with chimeric eCLIP

Mapping snoRNA-target RNA interactions in an RNA-binding protein-dependent manner with chimeric eCLIP

Abstract Background Small nucleolar RNAs (snoRNAs) are non-coding RNAs that function in ribosome and spliceosome biogenesis, primarily by guiding modifying enzymes to specific sites on ribosomal RNA (rRNA) and spliceosomal RNA (snRNA). However, many orphan snoRNAs remain uncharacterized, with uniden...

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Main Authors: Zhuoyi Song, Bongmin Bae, Simon Schnabl, Fei Yuan, Thareendra De Zoysa, Maureen V. Akinyi, Charlotte A. Le Roux, Karine Choquet, Amanda J. Whipple, Eric L. Van Nostrand
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-025-03508-7
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