Basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55-year-old male: A case report and review of literature

We report here a case of nevus sebaceous in a 55-year-old male, who presented with a 50-year history of an asymptomatic swelling in his right scalp. The solitary, yellowish, expansile plaque over the scalp gradually became lobulated and turned dark-pigmented with spontaneous bleeding, itching discom...

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Main Authors: Limin Luo, Jianjun Qiao, Hong Fang, Jun Li
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Photodiagnosis and Photodynamic Therapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S1572100023006890
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author Limin Luo
Jianjun Qiao
Hong Fang
Jun Li
author_facet Limin Luo
Jianjun Qiao
Hong Fang
Jun Li
author_sort Limin Luo
collection DOAJ
description We report here a case of nevus sebaceous in a 55-year-old male, who presented with a 50-year history of an asymptomatic swelling in his right scalp. The solitary, yellowish, expansile plaque over the scalp gradually became lobulated and turned dark-pigmented with spontaneous bleeding, itching discomfort, and occasional ulceration after scratching. The male's clinical presentation and histopathological findings were compatible with basal cell carcinoma arising in nevus sebaceous. At present, 5-aminolevulinic acid photodynamic therapy (ALA-PDT) emerges as a novel treatment modality which has proved safe and effective. In this case, three sessions of photodynamic therapy in combination with surgical excision were performed, leaving mild pigmentation within 3 weeks. The patient showed good cosmetic outcome, minimal scarring on the right scalp without further complications, disease recurrence or metastasis after ALA-PDT within six months.
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issn 1572-1000
language English
publishDate 2024-02-01
publisher Elsevier
record_format Article
series Photodiagnosis and Photodynamic Therapy
spelling doaj-art-27c2528fa65a4788827d36a0996a31402024-12-11T05:55:31ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002024-02-0145103960Basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55-year-old male: A case report and review of literatureLimin Luo0Jianjun Qiao1Hong Fang2Jun Li3Department of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Dermatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Cardiology, The First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China; Corresponding author.We report here a case of nevus sebaceous in a 55-year-old male, who presented with a 50-year history of an asymptomatic swelling in his right scalp. The solitary, yellowish, expansile plaque over the scalp gradually became lobulated and turned dark-pigmented with spontaneous bleeding, itching discomfort, and occasional ulceration after scratching. The male's clinical presentation and histopathological findings were compatible with basal cell carcinoma arising in nevus sebaceous. At present, 5-aminolevulinic acid photodynamic therapy (ALA-PDT) emerges as a novel treatment modality which has proved safe and effective. In this case, three sessions of photodynamic therapy in combination with surgical excision were performed, leaving mild pigmentation within 3 weeks. The patient showed good cosmetic outcome, minimal scarring on the right scalp without further complications, disease recurrence or metastasis after ALA-PDT within six months.http://www.sciencedirect.com/science/article/pii/S1572100023006890Basal cell carcinomaNevus sebaceousCase reportPhotodynamic therapy
spellingShingle Limin Luo
Jianjun Qiao
Hong Fang
Jun Li
Basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55-year-old male: A case report and review of literature
Photodiagnosis and Photodynamic Therapy
Basal cell carcinoma
Nevus sebaceous
Case report
Photodynamic therapy
title Basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55-year-old male: A case report and review of literature
title_full Basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55-year-old male: A case report and review of literature
title_fullStr Basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55-year-old male: A case report and review of literature
title_full_unstemmed Basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55-year-old male: A case report and review of literature
title_short Basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55-year-old male: A case report and review of literature
title_sort basal cell carcinoma arising within nevus sebaceous on the right scalp in a 55 year old male a case report and review of literature
topic Basal cell carcinoma
Nevus sebaceous
Case report
Photodynamic therapy
url http://www.sciencedirect.com/science/article/pii/S1572100023006890
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AT jianjunqiao basalcellcarcinomaarisingwithinnevussebaceousontherightscalpina55yearoldmaleacasereportandreviewofliterature
AT hongfang basalcellcarcinomaarisingwithinnevussebaceousontherightscalpina55yearoldmaleacasereportandreviewofliterature
AT junli basalcellcarcinomaarisingwithinnevussebaceousontherightscalpina55yearoldmaleacasereportandreviewofliterature