A clinicopathological study of diabetic retinopathy and biopsy-proven diabetic kidney disease in patients with type 2 diabetes
Objective We aimed to examine the clinical and pathological association between diabetic retinopathy（DR） and diabetic kidney disease（DKD） in type 2 diabetes mellitus（T2 DM） population,and discuss histopathologically.Methods A total of 70 patients with T2 DM and biopsy-proven DKD and complete DR were...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2020-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57906715&Fpath=home&index=0 |
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| Summary: | Objective We aimed to examine the clinical and pathological association between diabetic retinopathy（DR） and diabetic kidney disease（DKD） in type 2 diabetes mellitus（T2 DM） population,and discuss histopathologically.Methods A total of 70 patients with T2 DM and biopsy-proven DKD and complete DR were selected to conduct a cross-sectional study of their clinicopathological data.Results The differences between DR group and systolic blood pressure,hemoglobin,albumin,24-hour urinary protein and acute kidney injury were statistically significant（P<0.01）.The DR group was positively correlated with the DKD pathological grading（r=0.486） and Kimmelstiel-Wilson lesion（r=0.408）（P<0.01）.Diabetic macular edema was positively correlated with arteriolar hyalinosis（r=0.351） and microhemangioma（r=0.341）（P<0.01）.Conclusions It is possible to assess the clinical and pathological changes in DKD by the severity of DR. |
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| ISSN: | 1671-2390 |