Effect of acadesine on breast cancer cells under hypoxia
The riboside derivative acadesine (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) is currently being tested in clinical trials as a promising anti-tumor drug. Intracellular target of acadesine is adenosine monophosphate-activated protein kinase (АМРК), an important regulatory molecule of energ...
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| Main Authors: | A. M. Shcherbakov, N. E. Vavilov, O. E. Andreeva, B. V. Tyaglov, A. S. Mironov, R. S. Shakulov, K. V. Lobanov, S. V. Yarotskiy, A. A. Shtil’ |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2017-04-01
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| Series: | Успехи молекулярной онкологии |
| Subjects: | |
| Online Access: | https://umo.abvpress.ru/jour/article/view/90 |
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