The impact of combining cetuximab with the traditional chemotherapy regimens on clinical effectiveness in metastatic colorectal cancer: a systematic review and meta-analysis

The impact of combining cetuximab with the traditional chemotherapy regimens on clinical effectiveness in metastatic colorectal cancer: a systematic review and meta-analysis

Abstract Background Metastatic colorectal cancer (mCRC) poses a high rate of morbidity and mortality despite various treatment advances. Cetuximab, an anti-EGFR, has shown promising efficacy in improving outcomes when combined with chemotherapy. Understanding its efficacy is essential for optimizing...

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Main Authors: Marryam Azeem, Anees ur Rehman, Saba Rasheed, Aleena Shahzad, Muhammad Hamza Javed, Qurratul Ain Jamil, Hidayah Karuniawati, Saleh Karamah Al-Tamimi
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
Cetuximab
Chemotherapy
Anti-EGFR
Progression-free Survival
Overall Survival
Metastatic Colorectal Cancer
Online Access:https://doi.org/10.1186/s12885-025-13515-3
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