Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsions
The main trends in the use of liposomes or lipid aggregates as pseudostationary phases in capillary electrokinetic chromatography (EKC) over the past 15 years are reviewed. Due to the ability of liposomes to mimic cell membranes, they have found wide applications in analytical chemistry and especial...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-11-01
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| Series: | Journal of Chromatography Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772391724000501 |
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| author | Valeriia Lishchuk Susanne K. Wiedmer |
| author_facet | Valeriia Lishchuk Susanne K. Wiedmer |
| author_sort | Valeriia Lishchuk |
| collection | DOAJ |
| description | The main trends in the use of liposomes or lipid aggregates as pseudostationary phases in capillary electrokinetic chromatography (EKC) over the past 15 years are reviewed. Due to the ability of liposomes to mimic cell membranes, they have found wide applications in analytical chemistry and especially in the field of biomedical sciences. Various liposomes, lipid aggregates, and liposomal formulations have been adopted as background electrolytes in EKC and ultraviolet detection is by far the most commonly used detection mode. The possibility to vary the type of lipids and their content in the lipid aggregates has increasingly expanded the usage of liposome EKC for solving specific tasks. The presented data shows that there is great potential of liposome EKC in investigations of interactions between lipid membranes and compounds and the applications are typically related to biomedical and pharmaceutical issues, but not limited to these. |
| format | Article |
| id | doaj-art-27b51ff5e9be445faf03d972fd410764 |
| institution | OA Journals |
| issn | 2772-3917 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Chromatography Open |
| spelling | doaj-art-27b51ff5e9be445faf03d972fd4107642025-08-20T02:37:42ZengElsevierJournal of Chromatography Open2772-39172024-11-01610016310.1016/j.jcoa.2024.100163Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsionsValeriia Lishchuk0Susanne K. Wiedmer1Department of Chemistry, A.I. Virtasen aukio 1, POB 55, 00014 University of Helsinki, FinlandCorresponding author.; Department of Chemistry, A.I. Virtasen aukio 1, POB 55, 00014 University of Helsinki, FinlandThe main trends in the use of liposomes or lipid aggregates as pseudostationary phases in capillary electrokinetic chromatography (EKC) over the past 15 years are reviewed. Due to the ability of liposomes to mimic cell membranes, they have found wide applications in analytical chemistry and especially in the field of biomedical sciences. Various liposomes, lipid aggregates, and liposomal formulations have been adopted as background electrolytes in EKC and ultraviolet detection is by far the most commonly used detection mode. The possibility to vary the type of lipids and their content in the lipid aggregates has increasingly expanded the usage of liposome EKC for solving specific tasks. The presented data shows that there is great potential of liposome EKC in investigations of interactions between lipid membranes and compounds and the applications are typically related to biomedical and pharmaceutical issues, but not limited to these.http://www.sciencedirect.com/science/article/pii/S2772391724000501CapillaryElectrokinetic chromatographyIntralipidLipid emulsionLiposomesNanodisks |
| spellingShingle | Valeriia Lishchuk Susanne K. Wiedmer Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsions Journal of Chromatography Open Capillary Electrokinetic chromatography Intralipid Lipid emulsion Liposomes Nanodisks |
| title | Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsions |
| title_full | Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsions |
| title_fullStr | Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsions |
| title_full_unstemmed | Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsions |
| title_short | Recent trends in capillary electrokinetic chromatography with liposomes, lipid aggregates, and lipid emulsions |
| title_sort | recent trends in capillary electrokinetic chromatography with liposomes lipid aggregates and lipid emulsions |
| topic | Capillary Electrokinetic chromatography Intralipid Lipid emulsion Liposomes Nanodisks |
| url | http://www.sciencedirect.com/science/article/pii/S2772391724000501 |
| work_keys_str_mv | AT valeriialishchuk recenttrendsincapillaryelectrokineticchromatographywithliposomeslipidaggregatesandlipidemulsions AT susannekwiedmer recenttrendsincapillaryelectrokineticchromatographywithliposomeslipidaggregatesandlipidemulsions |