Single-cell RNA sequencing and multi-omics analysis of prognosis-related staging in papillary thyroid cancer

Single-cell RNA sequencing and multi-omics analysis of prognosis-related staging in papillary thyroid cancer

Abstract Background Papillary thyroid cancer (PTC) is the most common thyroid cancer, but current molecular features inadequately stratify its risk. Whether distinct underlying mechanisms can further classify PTC and improve prognostic precision remains unclear. Methods We integrated single-cell RNA...

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Bibliographic Details
Main Authors: Guo Ji, Hanlin Sun, Simo Chen, Xuechen Sun, Le Chang, Ruting Xie, Runzhi Huang, Lijun Zheng, Zhengyan Chang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Papillary thyroid cancer
Single-cell RNA sequencing
Molecular subtypes
Multi-omics
Online Access:https://doi.org/10.1007/s00262-025-04101-4
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