Gas Chromatographic/Mass Spectrometric Analysis of Volatile Metabolites in Bovine Vaginal Fluid and Assessment of Their Bioactivity

The chemical profiles of vaginal fluid collected from cows in oestrus and nonoestrus were analysed by gas chromatography-mass spectrometry (GC-MS) to establish any qualitative differences that might have p...

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Main Authors: R. Sankar, G. Archunan
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2011/256106
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author R. Sankar
G. Archunan
author_facet R. Sankar
G. Archunan
author_sort R. Sankar
collection DOAJ
description The chemical profiles of vaginal fluid collected from cows in oestrus and nonoestrus were analysed by gas chromatography-mass spectrometry (GC-MS) to establish any qualitative differences that might have potential value in bovine biocommunication. Eight different organic compounds were detected using the two chromatograms. The chemical profiles of oestrus vaginal fluid were distinguished significantly by the presence of three specific substances, namely, trimethylamine, acetic acid, and propionic acid that were not present in nonoestrus phase. The oestrus specific synthetic compounds were rubbed onto the genital region of nonoestrus animals (dummy cows), and the bulls were allowed to sniff the genital region and observed sexual behaviours. The statistical significance was higher (P<0.001) in bulls exhibiting repeated flehmen and mounting behaviours towards the mixture of acetic acid, propionic acid, and trimethylamine as compared to test these compounds separately. It was concluded that the volatile substances present in the bovine vaginal fluid during oestrus may act as chemical communicators.
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spelling doaj-art-2796ffde99b147108b2b3aa59ececc972025-08-20T03:54:57ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792011-01-01201110.1155/2011/256106256106Gas Chromatographic/Mass Spectrometric Analysis of Volatile Metabolites in Bovine Vaginal Fluid and Assessment of Their BioactivityR. Sankar0G. Archunan1Department of Animal Science, Bharathidasan University, Tiruchirappalli 620 024, IndiaDepartment of Animal Science, Bharathidasan University, Tiruchirappalli 620 024, IndiaThe chemical profiles of vaginal fluid collected from cows in oestrus and nonoestrus were analysed by gas chromatography-mass spectrometry (GC-MS) to establish any qualitative differences that might have potential value in bovine biocommunication. Eight different organic compounds were detected using the two chromatograms. The chemical profiles of oestrus vaginal fluid were distinguished significantly by the presence of three specific substances, namely, trimethylamine, acetic acid, and propionic acid that were not present in nonoestrus phase. The oestrus specific synthetic compounds were rubbed onto the genital region of nonoestrus animals (dummy cows), and the bulls were allowed to sniff the genital region and observed sexual behaviours. The statistical significance was higher (P<0.001) in bulls exhibiting repeated flehmen and mounting behaviours towards the mixture of acetic acid, propionic acid, and trimethylamine as compared to test these compounds separately. It was concluded that the volatile substances present in the bovine vaginal fluid during oestrus may act as chemical communicators.http://dx.doi.org/10.1155/2011/256106
spellingShingle R. Sankar
G. Archunan
Gas Chromatographic/Mass Spectrometric Analysis of Volatile Metabolites in Bovine Vaginal Fluid and Assessment of Their Bioactivity
International Journal of Analytical Chemistry
title Gas Chromatographic/Mass Spectrometric Analysis of Volatile Metabolites in Bovine Vaginal Fluid and Assessment of Their Bioactivity
title_full Gas Chromatographic/Mass Spectrometric Analysis of Volatile Metabolites in Bovine Vaginal Fluid and Assessment of Their Bioactivity
title_fullStr Gas Chromatographic/Mass Spectrometric Analysis of Volatile Metabolites in Bovine Vaginal Fluid and Assessment of Their Bioactivity
title_full_unstemmed Gas Chromatographic/Mass Spectrometric Analysis of Volatile Metabolites in Bovine Vaginal Fluid and Assessment of Their Bioactivity
title_short Gas Chromatographic/Mass Spectrometric Analysis of Volatile Metabolites in Bovine Vaginal Fluid and Assessment of Their Bioactivity
title_sort gas chromatographic mass spectrometric analysis of volatile metabolites in bovine vaginal fluid and assessment of their bioactivity
url http://dx.doi.org/10.1155/2011/256106
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