ABO phenotype and clinical correlates of COVID-19 severity in hospitalized patients

Aim: This study investigates the association between ABO blood phenotype and COVID-19 severity, measured by intensive care unit admission, need for intubation, hospitalization length and death. It further explores clinical predictors of COVID-19 severity within a primarily Hispanic demographic in Sa...

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Bibliographic Details
Main Authors: David J Hermel, Samantha R Spierling Bagsic, Carrie L Costantini, James R Mason, Zhubin J Gahvari, Alan Saven
Format: Article
Language:English
Published: Taylor & Francis Group 2021-09-01
Series:Future Science OA
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Online Access:https://www.future-science.com/doi/10.2144/fsoa-2021-0045
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Summary:Aim: This study investigates the association between ABO blood phenotype and COVID-19 severity, measured by intensive care unit admission, need for intubation, hospitalization length and death. It further explores clinical predictors of COVID-19 severity within a primarily Hispanic demographic in San Diego County. Materials & methods: We retrospectively reviewed 942 total patients, 473 with available blood type, hospitalized at five Scripps Health hospitals with COVID-19. Results: No significant association was found between ABO phenotype and COVID-19 severity on multivariate analysis, while a diagnosis of anemia and male sex was associated with all severity outcomes on exploratory analysis. Conclusion: Our results provide relevant clinical correlates of COVID-19 severity and help better elucidate the association between ABO phenotype and COVID-19.
ISSN:2056-5623