"Two shots for life. HPV-vaccination at your school". Co-creation of a complex intervention to reduce ethnic inequity in childhood HPV-vaccination in Denmark.

Despite free access to HPV-vaccination, adolescents with an ethnic minority background have an overall lower vaccination coverage due to various barriers needed to be accommodated in a targeted effort. We aim to report the development process of an intervention to increase HPV-vaccination coverage a...

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Main Authors: Anne Katrine Leonhard, Sara Koed Badre-Esfahani, Mette Bach Larsen, Lone Kjeld Petersen, Lene Seibæk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0323870
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author Anne Katrine Leonhard
Sara Koed Badre-Esfahani
Mette Bach Larsen
Lone Kjeld Petersen
Lene Seibæk
author_facet Anne Katrine Leonhard
Sara Koed Badre-Esfahani
Mette Bach Larsen
Lone Kjeld Petersen
Lene Seibæk
author_sort Anne Katrine Leonhard
collection DOAJ
description Despite free access to HPV-vaccination, adolescents with an ethnic minority background have an overall lower vaccination coverage due to various barriers needed to be accommodated in a targeted effort. We aim to report the development process of an intervention to increase HPV-vaccination coverage among adolescents with an ethnic minority background. An iterative co-creation guided by Medical Research Council UK development of complex interventions framework was done. We involved stakeholders throughout the process from the analysis of intervention interest and impact. The development process is described in four phases: 1) Evidence synthesis with focus-group interviews and literature review 2) Acceptability with stakeholders, 3) Elements and context with creation of a logic model, and finally 4) Co-production of material. The final intervention, "Two shots for life", is a school-based intervention consisting of HPV-education targeting adolescents and parents and HPV-vaccination at school during school hours. The intervention was designed to require the fewest possible resources for implementation sites, being municipality schools with a proportion of pupils >25% with ethnic minority background. Communication focus is HPV-vaccination as a prevention effort, it is mainly delivered face-to-face and written material is available in relevant minority languages as well as visual in appearance. A combined intervention with both educational and logistical components created with stakeholders is expected to accommodate barriers for HPV-vaccination in ethnic minority communities and increase accessibility and, hence, coverage of HPV-vaccination. By presenting a thorough development process, we expect to achieve transparency that will support future development of similar complex interventions aiming to increase HPV-vaccination coverage among ethnic minorities. ClinicalTrials.gov NCT05681169.
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spelling doaj-art-277babd9fca44879963b47b27afaff962025-08-23T05:32:28ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01208e032387010.1371/journal.pone.0323870"Two shots for life. HPV-vaccination at your school". Co-creation of a complex intervention to reduce ethnic inequity in childhood HPV-vaccination in Denmark. Anne Katrine LeonhardSara Koed Badre-EsfahaniMette Bach LarsenLone Kjeld PetersenLene SeibækDespite free access to HPV-vaccination, adolescents with an ethnic minority background have an overall lower vaccination coverage due to various barriers needed to be accommodated in a targeted effort. We aim to report the development process of an intervention to increase HPV-vaccination coverage among adolescents with an ethnic minority background. An iterative co-creation guided by Medical Research Council UK development of complex interventions framework was done. We involved stakeholders throughout the process from the analysis of intervention interest and impact. The development process is described in four phases: 1) Evidence synthesis with focus-group interviews and literature review 2) Acceptability with stakeholders, 3) Elements and context with creation of a logic model, and finally 4) Co-production of material. The final intervention, "Two shots for life", is a school-based intervention consisting of HPV-education targeting adolescents and parents and HPV-vaccination at school during school hours. The intervention was designed to require the fewest possible resources for implementation sites, being municipality schools with a proportion of pupils >25% with ethnic minority background. Communication focus is HPV-vaccination as a prevention effort, it is mainly delivered face-to-face and written material is available in relevant minority languages as well as visual in appearance. A combined intervention with both educational and logistical components created with stakeholders is expected to accommodate barriers for HPV-vaccination in ethnic minority communities and increase accessibility and, hence, coverage of HPV-vaccination. By presenting a thorough development process, we expect to achieve transparency that will support future development of similar complex interventions aiming to increase HPV-vaccination coverage among ethnic minorities. ClinicalTrials.gov NCT05681169.https://doi.org/10.1371/journal.pone.0323870
spellingShingle Anne Katrine Leonhard
Sara Koed Badre-Esfahani
Mette Bach Larsen
Lone Kjeld Petersen
Lene Seibæk
"Two shots for life. HPV-vaccination at your school". Co-creation of a complex intervention to reduce ethnic inequity in childhood HPV-vaccination in Denmark.
PLoS ONE
title "Two shots for life. HPV-vaccination at your school". Co-creation of a complex intervention to reduce ethnic inequity in childhood HPV-vaccination in Denmark.
title_full "Two shots for life. HPV-vaccination at your school". Co-creation of a complex intervention to reduce ethnic inequity in childhood HPV-vaccination in Denmark.
title_fullStr "Two shots for life. HPV-vaccination at your school". Co-creation of a complex intervention to reduce ethnic inequity in childhood HPV-vaccination in Denmark.
title_full_unstemmed "Two shots for life. HPV-vaccination at your school". Co-creation of a complex intervention to reduce ethnic inequity in childhood HPV-vaccination in Denmark.
title_short "Two shots for life. HPV-vaccination at your school". Co-creation of a complex intervention to reduce ethnic inequity in childhood HPV-vaccination in Denmark.
title_sort two shots for life hpv vaccination at your school co creation of a complex intervention to reduce ethnic inequity in childhood hpv vaccination in denmark
url https://doi.org/10.1371/journal.pone.0323870
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